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Journal / Cancer Research / Multiplexed ayirt analizi ve Intratumoral PD-1+…
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Cancer Research

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JoVE Journal Cancer Research
Multiplexed ayirt analizi ve Intratumoral PD-1+ Tim-3+ CD8 miktar+ T hücreleri
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Multiplexed ayirt analizi ve Intratumoral PD-1+ Tim-3+ CD8 miktar+ T hücreleri

Article DOI: 10.3791/56606-v • 09:32 min • February 8th, 2018
February 8th, 2018 •
1, 2,3,4, 2,3, 2,3, 2,3,5, 6, 7, 2, 2, 2, 2,3,6, 8, 2,3, 4, 2,6, *4, *2,4
1PARCC-INSERM U970, Université Paris Descartes, 2INSERM U970, Université Paris Descartes, 3Equipe Labellisée Ligue Contre le Cancer, 4Department of Immunology, Hopital Européen Georges Pompidou, 5Department of Medical Urology, Hopital Européen Georges Pompidou, 6Department of Pathology, Hopital Européen Georges Pompidou, 7Université Paris Diderot Paris 7, 8Department of medical oncology, Hopital Européen Georges Pompidou
* These authors contributed equally

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Tümör microenvironment eğitim klinik yanıt immünoterapi prognostik veya akýllý biyolojik tespit edebilir. Burada sunulan, bir yöntem situ Floresans spektral analiz ve CD8 otomatik olarak çeşitli altgrupları saymak için görüntüleme üzerinde dayanır+ T hücreleri. Bu tekrarlanabilir ve güvenilir teknik büyük kohort analizi için uygundur.

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İmmünoloji sayı 132 Multiplex in situ spektral görüntüleme ayirt tekniği dijital görüntüleme renal hücreli karsinom Tim-3 PD-1 tümör microenvironment denetim noktası inhibitörleri in situ tek hücre analizi
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