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Bioprintable alginaat/gelatine Hydrogel 3D In Vitro modelsystemen induceren sferoïde celvorming
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Bioprintable alginaat/gelatine Hydrogel 3D In Vitro modelsystemen induceren sferoïde celvorming

Article DOI: 10.3791/57826-v • 16:20 min • July 2nd, 2018
July 2nd, 2018 •
*1, *2,3, 2, 4, 4, 3, 2,5
1Department of Mechanical Engineering, McGill University Montreal, 2Department of Bioengineering, McGill University Montreal, 3Department of Molecular Biology, Instituto Potosino de Investigación Científica y Tecnológica, A.C. (IPICyT), 4Department of Mining and Materials Engineering, McGill University Montreal, 5Department of Biomedical Engineering, McGill University Montreal
* These authors contributed equally

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Wij ontwikkeld een heterogene borst kanker model bestaande uit vereeuwigd tumor en fibroblast cellen ingebed in een bioprintable alginaat/gelatine bioink. Het model recapituleert de tumor in vivo communicatie en vergemakkelijkt de vorming van meercellige tumor spheroïden, inzicht in de mechanismen van tumorvorming rijden oplevert.

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Bioengineering kwestie 137 3D bioprinting hydrogel kankercellen tumor spheroïden alginaat gelatine
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