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Journal / Neuroscience / Romanen In Vitro modell for Blast traumatisk…
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Neuroscience

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JoVE Journal Neuroscience
Romanen In Vitro modell for Blast traumatisk hjerneskade
Recording Spatially Restricted Oscillations in the Hippocampus of Behaving Mice
Journal (Neuroscience)
Recording Spatially Restricted Oscillations in the Hippocampus of Behaving Mice
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Journal (Neuroscience)
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Romanen In Vitro modell for Blast traumatisk hjerneskade

Article DOI: 10.3791/58400-v • 08:59 min • December 21st, 2018
December 21st, 2018 •
1,2, 1, 2,3, 1, 4,5, 6, 1,2
1Anaesthetics, Pain Medicine and Intensive Care Section, Department of Surgery and Cancer, Imperial College London, 2Royal British Legion Centre for Blast Injury Studies, Department of Bioengineering, Imperial College London, 3Department of Bioengineering, Imperial College London, 4Department of Life Sciences, Imperial College London, 5Department of Anaesthetics, Royal Berkshire Hospital NHS Foundation Trust, 6Royal Centre for Defence Medicine, Medical Directorate Joint Force Command

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Dette dokumentet beskriver en ny modell av primære blast traumatisk hjerneskade. En komprimert luft drevet sjokk rør brukes til å utsette i vitro musen hippocampus skive kulturer til et enkelt sjokk bølge. Dette er en enkel og rask protokoll genererer en reproduserbar hjerneskade vev med en høy gjennomstrømning.

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Nevrovitenskap problemet 142 Blast traumatisk hjerneskade primære eksplosjon skader blast-indusert Biografiske filmer sjokk rør i vitro modell TBI organotypic hippocampus skive kulturer
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