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Trombocyt-baseret detektion af nitrogenoxid i blodet ved at måle VASP fosforylering
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Trombocyt-baseret detektion af nitrogenoxid i blodet ved at måle VASP fosforylering

Article DOI: 10.3791/58647-v • 07:13 min • January 7th, 2019
January 7th, 2019 •
1,2, 2, 2
1Department of Pharmacology, Faculty of Dentistry, Mahidol University, 2Molecular Medicine Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health

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Vi præsenterer her, en protokol for at løse den potentielle anvendelse af blodplader som en yderst følsom oxid sensor i blodet. Det beskriver indledende trombocyt udarbejdelse og anvendelse af nitrit og deoxygenated røde blodlegemer som nitrogenoxid generatorer.

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Medicin spørgsmål 143 blodplader røde blodlegemer nitrit nitrogenoxid blod koagulation deoxyhemoglobin VASP protein
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