This method was developed with the goal of delivering a steady drug solution via the carotid artery, to assess the pharmacokinetics of novel drugs in mouse models.
Jacobs, J. D., Hopper-Borge, E. A. Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice. J. Vis. Exp. (92), e51917, doi:10.3791/51917 (2014).