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High-throughput Nitrobenzoxadiazole-märkt kolesterol Efflux Assay
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High-throughput Nitrobenzoxadiazole-märkt kolesterol Efflux Assay

Article DOI: 10.3791/58891-v • 08:18 min • January 7th, 2019
January 7th, 2019 •
1, 1, 1
1Group of Genomics and Pharmacogenomics in HIV, Laboratory of Retrovirology and Viral Immunopathogenesis, IDIBAPS, Hospital Clínic de Barcelona

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Mätning av in vitro-kolesterol efflux kapacitet att serum eller plasma i makrofag cellmodeller är ett lovande verktyg som en biomarkör för åderförkalkning. I den aktuella studien, vi optimera och standardisera en fluorescerande NBD-kolesterol efflux metod och utveckla en hög genomströmning analys med 96 brunnar.

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Medicin fråga 143 NBD-kolesterol makrofager HDL kolesterolet efflux fluorescens apolipoprotein B-utarmat serum åderförkalkning omvänd kolesterol transport
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