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Induction de blessure pulmonaire de souris par injection endotrachéale de bleomycine
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Induction de blessure pulmonaire de souris par injection endotrachéale de bleomycine

Article DOI: 10.3791/58922-v • 06:52 min • April 30th, 2019
April 30th, 2019 •
*1, *2, 2, 2, 2, 3, 3, 1, 2, 2
1Servizio di Allevamento e Sperimentazione Animale, Polo ScientificoTecnologico, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS)-Istituto Nazionale Ricovero e Cura Anziani (INRCA), 2Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, 3UOS Centro di Terapia Cellulare "G. Lanzani", Azienda Socio Sanitaria Territoriale (ASST) Papa Giovanni XXIII
* These authors contributed equally

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Ici nous présentons une méthode efficace pour étudier l'activité antifibrotique des cellules stromal humaines infusées par voie intraveineuse injectées obtenues du cordon ombilical entier suivant l'induction des dommages de poumon par une injection endotracheal de bleomycin dans C57BL /6 souris. Ce protocole peut être facilement étendu aux tests précliniques d'autres traitements.

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Immunologie et infection numéro 146 bléomycine injection endotrachéale lésions pulmonaires cellules stromales mésenchymales du cordon ombilical humain (hUC-MSC) infusion de veine de queue c57BL/6 souris
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