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Journal / Biochemistry / Overvåking GPCR-β-arrestin1/2 interaksjoner i…
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Biochemistry

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JoVE Journal Biochemistry
Overvåking GPCR-β-arrestin1/2 interaksjoner i Real time levende systemer for å akselerere Drug Discovery
Using In Vitro Fluorescence Resonance Energy Transfer to Study the Dynamics Of Protein Complexes at a Millisecond Time Scale
Journal (Biochemistry)
Using In Vitro Fluorescence Resonance Energy Transfer to Study the Dynamics Of Protein Complexes at a Millisecond Time Scale
Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry
Journal (Biochemistry)
Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry
 
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Overvåking GPCR-β-arrestin1/2 interaksjoner i Real time levende systemer for å akselerere Drug Discovery

Article DOI: 10.3791/59994-v • 08:21 min • June 28th, 2019
June 28th, 2019 •
1, 1, 1, 1, 1
1Graduate School of Medicine, Korea University

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GPCR-β-arrestin interaksjoner er et voksende felt i GPCR narkotika funnet. Nøyaktige, presise og enkle å sette opp metoder er nødvendig for å overvåke slike interaksjoner i levende systemer. Vi viser en strukturell komplementering analysen for å overvåke GPCR-β-arrestin interaksjoner i sanntid levende celler, og det kan utvides til enhver GPCR.

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Biokjemi β-arrestins G-protein kombinert reseptorer narkotika funnet levende systemer sanntid strukturelle komplementering analysen narkotika utvikling
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