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Vurdering af de luftbårne partiklers akutte toksicitet ved indånding ved at udsætte dyrkede humane lungeceller ved luftflydende interface
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Vurdering af de luftbårne partiklers akutte toksicitet ved indånding ved at udsætte dyrkede humane lungeceller ved luftflydende interface

Article DOI: 10.3791/60572-v • 10:10 min • February 23rd, 2020
February 23rd, 2020 •
1, 2, 3, 2, 5, 3,4, 2, 2, 1, 3,4, 1,2
1Bundeswehr Institute of Pharmacology and Toxicology, 2Walther Straub Institute of Pharmacology and Toxicology, University of Munich, 3Cultex Laboratories GmbH, 4Cultex Technologies GmbH (formerly Cultex Laboratories GmbH), 5seh consulting + services

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Vi præsenterer et robust, overførbart og prædiktivt in vitro eksponeringssystem til screening og overvågning af luftbårne partikler vedrørende deres akutte lungecytotoksicitet ved at udsætte dyrkede menneskelige lungeceller på luftflydende interface (ALI).

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Medicin Akut lungetoksicitet in vitro eksponeringssystem luftflydende grænseflade validering cytotoksicitet luftbårne partikler
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