Bo-Jeng Wang Laboratory of Molecular Neurobiology, Institute of Cellular and Organismic Biology Academia Sinica Biography Publications Institution JoVE Articles Bo-Jeng Wang has not added a biography. If you are Bo-Jeng Wang and would like to personalize this page please email our Author Liaison for assistance. Publications Critical Roles of Dual-Specificity Phosphatases in Neuronal Proteostasis and Neurological Diseases International Journal of Molecular Sciences. Sep, 2017 | Pubmed ID: 28902166 VEGF Expression Correlates with Neuronal Differentiation and Predicts a Favorable Prognosis in Patients with Neuroblastoma Scientific Reports. Sep, 2017 | Pubmed ID: 28894229 ErbB2 Regulates Autophagic Flux to Modulate the Proteostasis of APP-CTFs in Alzheimer's Disease Proceedings of the National Academy of Sciences of the United States of America. Apr, 2017 | Pubmed ID: 28351972 Discovery of Small Molecular (D)-leucinamides As Potent, Notch-sparing γ-secretase Modulators European Journal of Medicinal Chemistry. May, 2014 | Pubmed ID: 24732790 Calreticulin Activates β1 Integrin Via Fucosylation by Fucosyltransferase 1 in J82 Human Bladder Cancer Cells The Biochemical Journal. May, 2014 | Pubmed ID: 24593306 Aryl Hydrocarbon Receptor Downregulates MYCN Expression and Promotes Cell Differentiation of Neuroblastoma PloS One. 2014 | Pubmed ID: 24586395 Presenilin-1 Regulates the Expression of P62 to Govern P62-dependent Tau Degradation Molecular Neurobiology. Feb, 2014 | Pubmed ID: 23794287 Retinoic Acid-elicited RARα/RXRα Signaling Attenuates Aβ Production by Directly Inhibiting γ-secretase-mediated Cleavage of Amyloid Precursor Protein ACS Chemical Neuroscience. Jul, 2013 | Pubmed ID: 23530929 Autophagy: a Double-edged Sword in Alzheimer's Disease Journal of Biosciences. Mar, 2012 | Pubmed ID: 22357213 Caveolin-1 Regulates γ-secretase-mediated AβPP Processing by Modulating Spatial Distribution of γ-secretase in Membrane Journal of Alzheimer's Disease : JAD. 2010 | Pubmed ID: 20847442 Tumor Necrosis Factor-alpha-elicited Stimulation of Gamma-secretase is Mediated by C-Jun N-terminal Kinase-dependent Phosphorylation of Presenilin and Nicastrin Molecular Biology of the Cell. Oct, 2008 | Pubmed ID: 18667537 Sodium Selenite Inhibits Gamma-secretase Activity Through Activation of ERK Neuroscience Letters. Jul, 2008 | Pubmed ID: 18547722 Unnatural Amino Acid-substituted (hydroxyethyl)urea Peptidomimetics Inhibit Gamma-secretase and Promote the Neuronal Differentiation of Neuroblastoma Cells Molecular Pharmacology. Feb, 2007 | Pubmed ID: 17105873 Tumor Necrosis Factor-alpha, Interleukin-1beta, and Interferon-gamma Stimulate Gamma-secretase-mediated Cleavage of Amyloid Precursor Protein Through a JNK-dependent MAPK Pathway The Journal of Biological Chemistry. Nov, 2004 | Pubmed ID: 15347683 Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms Bo-Jeng Wang*1, Pei-Yi Wu*1, Yun-Wen Chen*1, Yu-Tzu Chang1, Noopur Bhore1, Po-Fan Wu1, Yung-Feng Liao1 1Laboratory of Molecular Neurobiology, Institute of Cellular and Organismic Biology, Academia Sinica JoVE 56795 Neuroscience
Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms Bo-Jeng Wang*1, Pei-Yi Wu*1, Yun-Wen Chen*1, Yu-Tzu Chang1, Noopur Bhore1, Po-Fan Wu1, Yung-Feng Liao1 1Laboratory of Molecular Neurobiology, Institute of Cellular and Organismic Biology, Academia Sinica JoVE 56795 Neuroscience