Brigitte Guérin

Publications

• Evaluation of a Novel GRPR Antagonist for Prostate Cancer PET Imaging: [Cu]-DOTHA-PEG-RM26
  Nuclear Medicine and Biology. Jan, 2018  |   Pubmed ID: 29154145
• Improved Estrogen Receptor Assessment by PET Using the Novel RadiotracerF-4FMFES in Estrogen Receptor-Positive Breast Cancer Patients: An Ongoing Phase II Clinical Trial
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Feb, 2018  |   Pubmed ID: 28798032
• Targeting IL-5Rα with Antibody-conjugates Reveals a Strategy for Imaging and Therapy for Invasive Bladder Cancer
  Oncoimmunology. 2017  |   Pubmed ID: 29123949
• Synthesis and Spectral Properties of Estrogen- and Androgen-BODIPY Conjugates
  Steroids. Jul, 2017  |   Pubmed ID: 28483507
• Synthesis and Evaluation of a (64)Cu-Conjugate, a Selective δ-Opioid Receptor Positron Emission Tomography Imaging Agent
  Organic Letters. Apr, 2017  |   Pubmed ID: 28368122
• PACE4 is an Important Driver of ZR-75-1 Estrogen Receptor-positive Breast Cancer Proliferation and Tumor Progression
  European Journal of Cell Biology. Mar, 2017  |   Pubmed ID: 28347547
• Dietary Fatty Acid Metabolism of Brown Adipose Tissue in Cold-acclimated Men
  Nature Communications. Jan, 2017  |   Pubmed ID: 28134339
• Impact of Dianionic and Dicationic Linkers on Tumor Uptake and Biodistribution of [(64) Cu]Cu/NOTA Peptide-based Gastrin-releasing Peptide Receptors Antagonists
  Journal of Labelled Compounds & Radiopharmaceuticals. Apr, 2017  |   Pubmed ID: 28129446
• Inhibition of Intracellular Triglyceride Lipolysis Suppresses Cold-Induced Brown Adipose Tissue Metabolism and Increases Shivering in Humans
  Cell Metabolism. Feb, 2017  |   Pubmed ID: 28089568
• BODIPY-17α-ethynylestradiol Conjugates: Synthesis, Fluorescence Properties and Receptor Binding Affinities
  Bioorganic & Medicinal Chemistry Letters. Feb, 2017  |   Pubmed ID: 28049591
• Synthesis of Gly-ψ[(Z)CF═CH]-Phe, a Fluoroalkene Dipeptide Isostere, and Its Incorporation into a Leu-enkephalin Peptidomimetic
  ACS Chemical Neuroscience. Jan, 2017  |   Pubmed ID: 27762555
• Clinical Trial with Sodium (99m)Tc-Pertechnetate Produced by a Medium-Energy Cyclotron: Biodistribution and Safety Assessment in Patients with Abnormal Thyroid Function
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. May, 2017  |   Pubmed ID: 27738005
• Increased Radiosensitivity of Colorectal Tumors with Intra-tumoral Injection of Low Dose of Gold Nanoparticles
  International Journal of Nanomedicine. 2016  |   Pubmed ID: 27789945
• Targeting the Neuropeptide Y1 Receptor for Cancer Imaging by Positron Emission Tomography Using Novel Truncated Peptides
  Molecular Pharmaceutics. Nov, 2016  |   Pubmed ID: 27669056
• Seven-Day Caloric and Saturated Fat Restriction Increases Myocardial Dietary Fatty Acid Partitioning in Impaired Glucose-Tolerant Subjects
  Diabetes. Nov, 2015  |   Pubmed ID: 26224886
• Radioisotopic Purity of Sodium Pertechnetate 99mTc Produced with a Medium-Energy Cyclotron: Implications for Internal Radiation Dose, Image Quality, and Release Specifications
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Oct, 2015  |   Pubmed ID: 26205300
• Multi-Leu PACE4 Inhibitor Retention Within Cells Is PACE4 Dependent and a Prerequisite for Antiproliferative Activity
  BioMed Research International. 2015  |   Pubmed ID: 26114115
• PACE4 Inhibitors and Their Peptidomimetic Analogs Block Prostate Cancer Tumor Progression Through Quiescence Induction, Increased Apoptosis and Impaired Neovascularisation
  Oncotarget. Feb, 2015  |   Pubmed ID: 25682874
• Selective Impairment of Glucose but Not Fatty Acid or Oxidative Metabolism in Brown Adipose Tissue of Subjects With Type 2 Diabetes
  Diabetes. Jul, 2015  |   Pubmed ID: 25677914
• Effect of Sex and Impaired Glucose Tolerance on Organ-Specific Dietary Fatty Acid Metabolism in Humans
  Diabetes. Jul, 2015  |   Pubmed ID: 25503741
• Contributions of White and Brown Adipose Tissues and Skeletal Muscles to Acute Cold-induced Metabolic Responses in Healthy Men
  The Journal of Physiology. Feb, 2015  |   Pubmed ID: 25384777
• PACE4-based Molecular Targeting of Prostate Cancer Using an Engineered ⁶⁴Cu-radiolabeled Peptide Inhibitor
  Neoplasia (New York, N.Y.). Aug, 2014  |   Pubmed ID: 25220591
• Development of Bifunctional Chelates Bearing Hydroxamate Arms for Highly Efficient (64)Cu Radiolabeling
  Organic Letters. Sep, 2014  |   Pubmed ID: 25133292
• Improved Cardiac Function and Dietary Fatty Acid Metabolism After Modest Weight Loss in Subjects with Impaired Glucose Tolerance
  American Journal of Physiology. Endocrinology and Metabolism. Jun, 2014  |   Pubmed ID: 24760989
• Increased Brown Adipose Tissue Oxidative Capacity in Cold-acclimated Humans
  The Journal of Clinical Endocrinology and Metabolism. Mar, 2014  |   Pubmed ID: 24423363
• Copper Transport and Regulation in Schizosaccharomyces Pombe
  Biochemical Society Transactions. Dec, 2013  |   Pubmed ID: 24256274
• Systematic Replacement of Amides by 1,4-disubstituted[1,2,3]triazoles in Leu-enkephalin and the Impact on the Delta Opioid Receptor Activity
  Bioorganic & Medicinal Chemistry Letters. Oct, 2013  |   Pubmed ID: 23988352
• (68)Ga/DOTA- and (64)Cu/NOTA-phthalocyanine Conjugates As Fluorescent/PET Bimodal Imaging Probes
  Bioconjugate Chemistry. Sep, 2013  |   Pubmed ID: 23978056
• 2-Fluoropyridine Prosthetic Compounds for the 18F Labeling of Bombesin Analogues
  Bioorganic & Medicinal Chemistry Letters. Jul, 2013  |   Pubmed ID: 23683595
• Preparation and Evaluation at the Delta Opioid Receptor of a Series of Linear Leu-enkephalin Analogues Obtained by Systematic Replacement of the Amides
  ACS Chemical Neuroscience. Aug, 2013  |   Pubmed ID: 23650868
• Phthalocyanine-peptide Conjugates: Receptor-targeting Bifunctional Agents for Imaging and Photodynamic Therapy
  Journal of Medicinal Chemistry. Feb, 2013  |   Pubmed ID: 23356907
• Increased Myocardial Uptake of Dietary Fatty Acids Linked to Cardiac Dysfunction in Glucose-intolerant Humans
  Diabetes. Nov, 2012  |   Pubmed ID: 23093657
• Sulfonyl Fluoride-based Prosthetic Compounds As Potential 18F Labelling Agents
  Chemistry (Weinheim an Der Bergstrasse, Germany). Aug, 2012  |   Pubmed ID: 22807282
• EP 80317, a Selective CD36 Ligand, Shows Cardioprotective Effects Against Post-ischaemic Myocardial Damage in Mice
  Cardiovascular Research. Oct, 2012  |   Pubmed ID: 22787133
• Novel Radiolabeled Peptides for Breast and Prostate Tumor PET Imaging: (64)Cu/and (68)Ga/NOTA-PEG-[D-Tyr(6),βAla(11),Thi(13),Nle(14)]BBN(6-14)
  Bioconjugate Chemistry. Aug, 2012  |   Pubmed ID: 22770480
• Comparative Study of 64Cu/NOTA-[D-Tyr6,βAla11,Thi13,Nle14]BBN(6-14) Monomer and Dimers for Prostate Cancer PET Imaging
  EJNMMI Research. 2012  |   Pubmed ID: 22333272
• Brown Adipose Tissue Oxidative Metabolism Contributes to Energy Expenditure During Acute Cold Exposure in Humans
  The Journal of Clinical Investigation. Feb, 2012  |   Pubmed ID: 22269323
• PET Imaging Using 64Cu-labeled Sulfophthalocyanines: Synthesis and Biodistribution
  Bioorganic & Medicinal Chemistry Letters. Dec, 2011  |   Pubmed ID: 22050887
• Mfc1 is a Novel Forespore Membrane Copper Transporter in Meiotic and Sporulating Cells
  The Journal of Biological Chemistry. Sep, 2011  |   Pubmed ID: 21828039
• Evaluation of 64Cu-labeled Bifunctional Chelate-bombesin Conjugates
  Bioconjugate Chemistry. Aug, 2011  |   Pubmed ID: 21761921
• Phthalocyanine-peptide Conjugates Via Palladium-catalyzed Cross-coupling Reactions
  The Journal of Organic Chemistry. Mar, 2011  |   Pubmed ID: 21302913
• Normal Postprandial Nonesterified Fatty Acid Uptake in Muscles Despite Increased Circulating Fatty Acids in Type 2 Diabetes
  Diabetes. Feb, 2011  |   Pubmed ID: 21228312
• Organ-specific Dietary Fatty Acid Uptake in Humans Using Positron Emission Tomography Coupled to Computed Tomography
  American Journal of Physiology. Endocrinology and Metabolism. Mar, 2011  |   Pubmed ID: 21098737
• Cyclotron Production of 99mTc: an Approach to the Medical Isotope Crisis
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Apr, 2010  |   Pubmed ID: 20351346
• [Lys(DOTA)4]BVD15, a Novel and Potent Neuropeptide Y Analog Designed for Y1 Receptor-targeted Breast Tumor Imaging
  Bioorganic & Medicinal Chemistry Letters. Feb, 2010  |   Pubmed ID: 20042335
• Total Solid-phase Synthesis of NOTA-functionalized Peptides for PET Imaging
  Organic Letters. Jan, 2010  |   Pubmed ID: 20014826
• New Enzyme-activated Solubility-switchable Contrast Agent for Magnetic Resonance Imaging: from Synthesis to in Vivo Imaging
  Journal of Medicinal Chemistry. Mar, 2009  |   Pubmed ID: 19228016
• Synthesis of Tertiary and Quaternary Stereogenic Centers: a Diastereoselective Tandem Reaction Sequence Combining Mukaiyama and Free Radical-based Allylation
  The Journal of Organic Chemistry. Feb, 2005  |   Pubmed ID: 15675832
• Enhanced Dermal and Retinal Vascular Permeability in Streptozotocin-induced Type 1 Diabetes in Wistar Rats: Blockade with a Selective Bradykinin B1 Receptor Antagonist
  Regulatory Peptides. Jan, 2005  |   Pubmed ID: 15544863
• Zinc Improves Gene Transfer Mediated by DNA/cationic Polymer Complexes
  The Journal of Gene Medicine. Sep-Oct, 2002  |   Pubmed ID: 12221648
• Intracellular Processing and Stability of DNA Complexed with Histidylated Polylysine Conjugates
  The Journal of Gene Medicine. May-Jun, 2002  |   Pubmed ID: 12112644
• Synthesis of 2,3-anti-3,4-anti and 2,3-anti-3,4-syn Propionate Motifs: a Diastereoselective Tandem Sequence of Mukaiyama and Free-radical-based Hydrogen Transfer Reactions
  Organic Letters. Mar, 2002  |   Pubmed ID: 11893211
• Synthesis of N-glycosides. An Alternative Approach Based on Diastereoselective Base Coupling and S(N)2 Cyclization
  Organic Letters. Jan, 2002  |   Pubmed ID: 11796060
• Poly[Lys-(AEDTP)]: a Cationic Polymer That Allows Dissociation of PDNA/cationic Polymer Complexes in a Reductive Medium and Enhances Polyfection
  Bioconjugate Chemistry. Jan-Feb, 2002  |   Pubmed ID: 11792180