Roger Lecomte

Publications

• Improved Estrogen Receptor Assessment by PET Using the Novel RadiotracerF-4FMFES in Estrogen Receptor-Positive Breast Cancer Patients: An Ongoing Phase II Clinical Trial
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Feb, 2018  |   Pubmed ID: 28798032
• Targeting IL-5Rα with Antibody-conjugates Reveals a Strategy for Imaging and Therapy for Invasive Bladder Cancer
  Oncoimmunology. 2017  |   Pubmed ID: 29123949
• The Loss of P2X7 Receptor Expression Leads to Increase Intestinal Glucose Transit and Hepatic Steatosis
  Scientific Reports. Oct, 2017  |   Pubmed ID: 29018292
• Loss of UCP2 Impairs Cold-induced Non-shivering Thermogenesis by Promoting a Shift Toward Glucose Utilization in Brown Adipose Tissue
  Biochimie. Mar, 2017  |   Pubmed ID: 28130074
• Impact of Dianionic and Dicationic Linkers on Tumor Uptake and Biodistribution of [(64) Cu]Cu/NOTA Peptide-based Gastrin-releasing Peptide Receptors Antagonists
  Journal of Labelled Compounds & Radiopharmaceuticals. Apr, 2017  |   Pubmed ID: 28129446
• A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate
  PloS One. 2017  |   Pubmed ID: 28129334
• Simulation of Scintillation Light Output in LYSO Scintillators Through a Full Factorial Design
  Physics in Medicine and Biology. Jan, 2017  |   Pubmed ID: 28050968
• Clinical Trial with Sodium (99m)Tc-Pertechnetate Produced by a Medium-Energy Cyclotron: Biodistribution and Safety Assessment in Patients with Abnormal Thyroid Function
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. May, 2017  |   Pubmed ID: 27738005
• MTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold
  Scientific Reports. Nov, 2016  |   Pubmed ID: 27876792
• Real-Time Microfluidic Blood-Counting System for PET and SPECT Preclinical Pharmacokinetic Studies
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Sep, 2016  |   Pubmed ID: 27151983
• Postprandial Fatty Acid Uptake and Adipocyte Remodeling in Angiotensin Type 2 Receptor-deficient Mice Fed a High-fat/high-fructose Diet
  Adipocyte. Jan-Mar, 2016  |   Pubmed ID: 27144096
• Metabolic Activity of Brown, "beige," and White Adipose Tissues in Response to Chronic Adrenergic Stimulation in Male Mice
  American Journal of Physiology. Endocrinology and Metabolism. Jul, 2016  |   Pubmed ID: 27143559
• Transcriptional Changes Associated with Long-Term Left Ventricle Volume Overload in Rats: Impact on Enzymes Related to Myocardial Energy Metabolism
  BioMed Research International. 2015  |   Pubmed ID: 26583150
• Multipinhole SPECT Helical Scan Parameters and Imaging Volume
  Medical Physics. Nov, 2015  |   Pubmed ID: 26520751
• Radioisotopic Purity of Sodium Pertechnetate 99mTc Produced with a Medium-Energy Cyclotron: Implications for Internal Radiation Dose, Image Quality, and Release Specifications
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Oct, 2015  |   Pubmed ID: 26205300
• A Real-time Follow-up of Photodynamic Therapy During PET Imaging
  Photodiagnosis and Photodynamic Therapy. Sep, 2015  |   Pubmed ID: 26007241
• [(18)F]-fluorodeoxyglucose Positron Emission Tomography of the Cat Brain: A Feasibility Study to Investigate Osteoarthritis-associated Pain
  Veterinary Journal (London, England : 1997). Jun, 2015  |   Pubmed ID: 25951988
• In Vivo Measurement of Energy Substrate Contribution to Cold-induced Brown Adipose Tissue Thermogenesis
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2015  |   Pubmed ID: 25681456
• Optimization of the Reference Region Method for Dual Pharmacokinetic Modeling Using Gd-DTPA/MRI and (18) F-FDG/PET
  Magnetic Resonance in Medicine. Feb, 2015  |   Pubmed ID: 24604379
• Endurance Training or Beta-blockade Can Partially Block the Energy Metabolism Remodeling Taking Place in Experimental Chronic Left Ventricle Volume Overload
  BMC Cardiovascular Disorders. Dec, 2014  |   Pubmed ID: 25518920
• A Longitudinal Low Dose μCT Analysis of Bone Healing in Mice: A Pilot Study
  Advances in Orthopedics. 2014  |   Pubmed ID: 25431676
• [(11)C]-Acetoacetate PET Imaging: a Potential Early Marker for Cardiac Heart Failure
  Nuclear Medicine and Biology. Nov-Dec, 2014  |   Pubmed ID: 25195015
• Deciphering PDT-induced Inflammatory Responses Using Real-time FDG-PET in a Mouse Tumour Model
  Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. Oct, 2014  |   Pubmed ID: 25058054
• Arterial Input Function Sampling Without Surgery in Rats for Positron Emission Tomography Molecular Imaging
  Nuclear Medicine Communications. Jun, 2014  |   Pubmed ID: 24594981
• Imaging Performance of LabPET APD-based Digital PET Scanners for Pre-clinical Research
  Physics in Medicine and Biology. Feb, 2014  |   Pubmed ID: 24442278
• Comment on "Temperature Dependence of APD-based PET Scanners" [Med. Phys. 40(9) 092506 (13pp.) (2013)]
  Medical Physics. Jan, 2014  |   Pubmed ID: 24387535
• Fully 3D Iterative CT Reconstruction Using Polar Coordinates
  Medical Physics. Nov, 2013  |   Pubmed ID: 24320437
• (68)Ga/DOTA- and (64)Cu/NOTA-phthalocyanine Conjugates As Fluorescent/PET Bimodal Imaging Probes
  Bioconjugate Chemistry. Sep, 2013  |   Pubmed ID: 23978056
• Angiotensin II-converting Enzyme Inhibition Improves Survival, Ventricular Remodeling, and Myocardial Energetics in Experimental Aortic Regurgitation
  Circulation. Heart Failure. Sep, 2013  |   Pubmed ID: 23861486
• Assessment of the Novel Estrogen Receptor PET Tracer 4-fluoro-11β-methoxy-16α-[(18)F]fluoroestradiol (4FMFES) by PET Imaging in a Breast Cancer Murine Model
  Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Oct, 2013  |   Pubmed ID: 23619898
• Mammary Cancer Bone Metastasis Follow-up Using Multimodal Small-animal MR and PET Imaging
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jun, 2013  |   Pubmed ID: 23596003
• PET-based Geometrical Calibration of a Pinhole SPECT Add-on for an Animal PET Scanner
  Physics in Medicine and Biology. Apr, 2013  |   Pubmed ID: 23458923
• Conversion of Arterial Input Functions for Dual Pharmacokinetic Modeling Using Gd-DTPA/MRI and 18F-FDG/PET
  Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Mar, 2013  |   Pubmed ID: 22570280
• Toward Truly Combined PET/CT Imaging Using PET Detectors and Photon Counting CT with Iterative Reconstruction Implementing Physical Detector Response
  Medical Physics. Sep, 2012  |   Pubmed ID: 28524989
• Quantitative Hormone Therapy Follow-up in an ER+/ERαKD Mouse Tumor Model Using FDG and [11C]-methionine PET Imaging
  EJNMMI Research. 2012  |   Pubmed ID: 23140372
• The Ketogenic Diet Increases Brain Glucose and Ketone Uptake in Aged Rats: a Dual Tracer PET and Volumetric MRI Study
  Brain Research. Dec, 2012  |   Pubmed ID: 23063891
• Blood Compatible Microfluidic System for Pharmacokinetic Studies in Small Animals
  Lab on a Chip. Nov, 2012  |   Pubmed ID: 23000896
• Toward Truly Combined PET/CT Imaging Using PET Detectors and Photon Counting CT with Iterative Reconstruction Implementing Physical Detector Response
  Medical Physics. Sep, 2012  |   Pubmed ID: 22957635
• EP 80317, a Selective CD36 Ligand, Shows Cardioprotective Effects Against Post-ischaemic Myocardial Damage in Mice
  Cardiovascular Research. Oct, 2012  |   Pubmed ID: 22787133
• Novel Radiolabeled Peptides for Breast and Prostate Tumor PET Imaging: (64)Cu/and (68)Ga/NOTA-PEG-[D-Tyr(6),βAla(11),Thi(13),Nle(14)]BBN(6-14)
  Bioconjugate Chemistry. Aug, 2012  |   Pubmed ID: 22770480
• NEMA NU 4-2008 Comparison of Preclinical PET Imaging Systems
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Aug, 2012  |   Pubmed ID: 22699999
• Small-animal PET: What is It, and Why Do We Need It?
  Journal of Nuclear Medicine Technology. Sep, 2012  |   Pubmed ID: 22582006
• Positron Emission Tomography Detection of Human Endothelial Cell and Fibroblast Monolayers: Effect of Pretreament and Cell Density on 18FDG Uptake
  Vascular Cell. 2012  |   Pubmed ID: 22433292
• Comparative Study of 64Cu/NOTA-[D-Tyr6,βAla11,Thi13,Nle14]BBN(6-14) Monomer and Dimers for Prostate Cancer PET Imaging
  EJNMMI Research. 2012  |   Pubmed ID: 22333272
• Predicting Efficacy of Photodynamic Therapy by Real-time FDG-PET in a Mouse Tumour Model
  Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology. Feb, 2012  |   Pubmed ID: 22234417
• [11C]Acetate Rest-stress Protocol to Assess Myocardial Perfusion and Oxygen Consumption Reserve in a Model of Congestive Heart Failure in Rats
  Nuclear Medicine and Biology. Feb, 2012  |   Pubmed ID: 22079038
• [18F]-fluoroestradiol Quantitative PET Imaging to Differentiate ER+ and ERα-knockdown Breast Tumors in Mice
  Nuclear Medicine and Biology. Jan, 2012  |   Pubmed ID: 22079037
• PET Imaging Using 64Cu-labeled Sulfophthalocyanines: Synthesis and Biodistribution
  Bioorganic & Medicinal Chemistry Letters. Dec, 2011  |   Pubmed ID: 22050887
• Mild Experimental Ketosis Increases Brain Uptake of 11C-acetoacetate and 18F-fluorodeoxyglucose: a Dual-tracer PET Imaging Study in Rats
  Nutritional Neuroscience. Mar, 2011  |   Pubmed ID: 21605500
• Mono- and Tri-cationic Porphyrin-monoclonal Antibody Conjugates: Photodynamic Activity and Mechanism of Action
  Immunology. Feb, 2011  |   Pubmed ID: 21039468
• Behavioral, Medical Imaging and Histopathological Features of a New Rat Model of Bone Cancer Pain
  PloS One. 2010  |   Pubmed ID: 21048940
• Image-derived Input Function in Dynamic Human PET/CT: Methodology and Validation with 11C-acetate and 18F-fluorothioheptadecanoic Acid in Muscle and 18F-fluorodeoxyglucose in Brain
  European Journal of Nuclear Medicine and Molecular Imaging. Aug, 2010  |   Pubmed ID: 20437239
• Cyclotron Production of 99mTc: an Approach to the Medical Isotope Crisis
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Apr, 2010  |   Pubmed ID: 20351346
• Abnormal in Vivo Myocardial Energy Substrate Uptake in Diet-induced Type 2 Diabetic Cardiomyopathy in Rats
  American Journal of Physiology. Endocrinology and Metabolism. May, 2010  |   Pubmed ID: 20159856
• A Pulse Simulator for Crystal Identification Validation of Phoswich Detectors Used in Positron Emission Tomography
  Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2009  |   Pubmed ID: 19964462
• PET Study of 11C-acetoacetate Kinetics in Rat Brain During Dietary Treatments Affecting Ketosis
  American Journal of Physiology. Endocrinology and Metabolism. Apr, 2009  |   Pubmed ID: 19176356
• Novel Detector Technology for Clinical PET
  European Journal of Nuclear Medicine and Molecular Imaging. Mar, 2009  |   Pubmed ID: 19107476
• Mechanism of Reduced Myocardial Glucose Utilization During Acute Hypertriglyceridemia in Rats
  Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Jan-Feb, 2009  |   Pubmed ID: 18769973
• [11C] Acetoacetate Utilization by Breast and Prostate Tumors: a PET and Biodistribution Study in Mice
  Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Jul-Aug, 2008  |   Pubmed ID: 18454299
• Comparison of Analytical and Algebraic 2D Tomographic Reconstruction Approaches for Irregularly Sampled MicroCT Data
  Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2007  |   Pubmed ID: 18002605
• Standardization and Detailed Characterization of the Syngeneic Fischer/F98 Glioma Model
  The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Aug, 2007  |   Pubmed ID: 17803026
• A New Tool for Molecular Imaging: the Microvolumetric Beta Blood Counter
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jul, 2007  |   Pubmed ID: 17574990
• A Small Animal Positron Emission Tomography Study of the Effect of Chemotherapy and Hormonal Therapy on the Uptake of 2-deoxy-2-[F-18]fluoro-D-glucose in Murine Models of Breast Cancer
  Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. May-Jun, 2007  |   Pubmed ID: 17334852
• PET Imaging of Apoptosis with (64)Cu-labeled Streptavidin Following Pretargeting of Phosphatidylserine with Biotinylated Annexin-V
  European Journal of Nuclear Medicine and Molecular Imaging. Feb, 2007  |   Pubmed ID: 17021816
• Dynamic Imaging of Transient Metabolic Processes by Small-animal PET for the Evaluation of Photosensitizers in Photodynamic Therapy of Cancer
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jul, 2006  |   Pubmed ID: 16818946
• The Effect of Insulin on the Intracellular Distribution of 14(R,S)-[18F]Fluoro-6-thia-heptadecanoic Acid in Rats
  Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Jul-Aug, 2006  |   Pubmed ID: 16791750
• Positron Emission Tomography Imaging of Tumor Response After Photodynamic Therapy
  Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society for Environmental Toxicology and Cancer. 2006  |   Pubmed ID: 16566721
• Endotoxin-induced Heart Dysfunction in Rats: Assessment of Myocardial Perfusion and Permeability and the Role of Fluid Resuscitation
  Critical Care Medicine. Jan, 2006  |   Pubmed ID: 16374166
• Quantitative Myocardial Perfusion and Coronary Reserve in Rats with 13N-ammonia and Small Animal PET: Impact of Anesthesia and Pharmacologic Stress Agents
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Nov, 2004  |   Pubmed ID: 15534064
• Breast Cancer Models to Study the Expression of Estrogen Receptors with Small Animal PET Imaging
  Nuclear Medicine and Biology. Aug, 2004  |   Pubmed ID: 15246367
• Respiratory Gating for 3-dimensional PET of the Thorax: Feasibility and Initial Results
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Feb, 2004  |   Pubmed ID: 14960638
• Quantitative Gated PET for the Assessment of Left Ventricular Function in Small Animals
  Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Oct, 2003  |   Pubmed ID: 14530482
• Assessment of Cancer-associated Biomarkers by Positron Emission Tomography: Advances and Challenges
  Disease Markers. 2002  |   Pubmed ID: 14646039