Douglas Grossman Department of Oncological Sciences and Huntsman Cancer Institute University of Utah School of Medicine Biography Publications Institution JoVE Articles Douglas Grossman has not added a biography. If you are Douglas Grossman and would like to personalize this page please email our Author Liaison for assistance. Publications A Phase II Randomized Placebo-Controlled Trial of Oral N-acetylcysteine for Protection of Melanocytic Nevi Against UV-Induced Oxidative Stress In Vivo Cancer Prevention Research (Philadelphia, Pa.). Jan, 2017 | Pubmed ID: 27920018 Development of an Educational Program Integrating Concepts of Genetic Risk and Preventive Strategies for Children with a Family History of Melanoma Journal of Cancer Education : the Official Journal of the American Association for Cancer Education. Nov, 2016 | Pubmed ID: 27889875 A Phase I Study of Intratumoral Ipilimumab and Interleukin-2 in Patients with Advanced Melanoma Oncotarget. Sep, 2016 | Pubmed ID: 27391442 Reduction in Nevus Biopsies in Patients Monitored by Total Body Photography Journal of the American Academy of Dermatology. Jul, 2016 | Pubmed ID: 26947450 Practical Application of New Technologies for Melanoma Diagnosis: Part II. Molecular Approaches Journal of the American Academy of Dermatology. Jun, 2015 | Pubmed ID: 25980999 Practical Application of New Technologies for Melanoma Diagnosis: Part I. Noninvasive Approaches Journal of the American Academy of Dermatology. Jun, 2015 | Pubmed ID: 25980998 A Safe and Efficient Model for Ultraviolet Radiation-induced Herpes Simplex Labialis Photodermatology, Photoimmunology & Photomedicine. May, 2015 | Pubmed ID: 25684629 Predictive Value of Biopsy Specimens Suspicious for Melanoma: Support for 6-mm Criterion in the ABCD Rule Journal of the American Academy of Dermatology. Mar, 2015 | Pubmed ID: 25582536 Addressing the Knowledge Gap in Clinical Recommendations for Management and Complete Excision of Clinically Atypical Nevi/dysplastic Nevi: Pigmented Lesion Subcommittee Consensus Statement JAMA Dermatology. Feb, 2015 | Pubmed ID: 25409291 Adequacy of 5-mm Surgical Excision Margins for Non-lentiginous Melanoma in Situ Journal of the American Academy of Dermatology. Oct, 2014 | Pubmed ID: 25219711 Aspirin and Other NSAIDs As Chemoprevention Agents in Melanoma Cancer Prevention Research (Philadelphia, Pa.). Jun, 2014 | Pubmed ID: 24694780 Skin Self-examinations and Visual Identification of Atypical Nevi: Comparing Individual and Crowdsourcing Approaches Cancer Epidemiology. Dec, 2013 | Pubmed ID: 24075797 Survivin Promotion of Melanoma Metastasis Requires Upregulation of α5 Integrin Carcinogenesis. Sep, 2013 | Pubmed ID: 23640047 Role of Melanin in Melanocyte Dysregulation of Reactive Oxygen Species BioMed Research International. 2013 | Pubmed ID: 23555101 Commentary: Transecting Melanomas: Does It Matter? Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]. Apr, 2013 | Pubmed ID: 23551555 Selenium for the Prevention of Cutaneous Melanoma Nutrients. Mar, 2013 | Pubmed ID: 23470450 Familial Melanoma-associated Mutations in P16 Uncouple Its Tumor-suppressor Functions The Journal of Investigative Dermatology. Apr, 2013 | Pubmed ID: 23190892 Sentinel Lymph Node Biopsy for Melanoma in Pregnant Women Annals of Surgical Oncology. Feb, 2013 | Pubmed ID: 23054111 Surgical Margins for Melanoma in Situ Journal of the American Academy of Dermatology. Nov, 2012 | Pubmed ID: 23062889 The Dysplastic Nevus: from Historical Perspective to Management in the Modern Era: Part II. Molecular Aspects and Clinical Management Journal of the American Academy of Dermatology. Jul, 2012 | Pubmed ID: 22703916 The Dysplastic Nevus: from Historical Perspective to Management in the Modern Era: Part I. Historical, Histologic, and Clinical Aspects Journal of the American Academy of Dermatology. Jul, 2012 | Pubmed ID: 22703915 Role of the Apoptotic and Mitotic Regulator Survivin in Melanoma Anticancer Research. Feb, 2012 | Pubmed ID: 22287725 A Decade of Melanomas: Identification of Factors Associated with Delayed Detection in an Academic Group Practice Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]. Nov, 2011 | Pubmed ID: 21790849 Failure to Compare Dermoscopy Findings of Pigmented Lesions on Your Patient: Comment on "Dermoscopy of Patients with Multiple Nevi" Archives of Dermatology. Jan, 2011 | Pubmed ID: 21242393 Survivin Enhances Motility of Melanoma Cells by Supporting Akt Activation and {alpha}5 Integrin Upregulation Cancer Research. Oct, 2010 | Pubmed ID: 20807805 Comparative Analysis of Total Body and Dermatoscopic Photographic Monitoring of Nevi in Similar Patient Populations at Risk for Cutaneous Melanoma Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]. Jul, 2010 | Pubmed ID: 20653722 Low Rates of Clinical Recurrence After Biopsy of Benign to Moderately Dysplastic Melanocytic Nevi Journal of the American Academy of Dermatology. Apr, 2010 | Pubmed ID: 20018406 Use of Oral N-acetylcysteine for Protection of Melanocytic Nevi Against UV-induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2009 | Pubmed ID: 19920101 Strategies for Early Melanoma Detection: Approaches to the Patient with Nevi Journal of the American Academy of Dermatology. May, 2009 | Pubmed ID: 19389517 The Marine Alkaloid Naamidine A Promotes Caspase-dependent Apoptosis in Tumor Cells Anti-cancer Drugs. Jul, 2009 | Pubmed ID: 19369860 Sampling of Melanocytic Nevi for Research Purposes: a Prospective, Pilot Study to Determine Effect on Diagnosis Journal of the American Academy of Dermatology. Nov, 2008 | Pubmed ID: 19119097 Role of Phospholipid Scramblase 3 in the Regulation of Tumor Necrosis Factor-alpha-induced Apoptosis Biochemistry. Apr, 2008 | Pubmed ID: 18358005 Increased Melanocytic Nevi and Nevus Density in a G-34T CDKN2A/p16 Melanoma-prone Pedigree The Journal of Investigative Dermatology. Aug, 2008 | Pubmed ID: 18337833 Survivin Repression by P53, Rb and E2F2 in Normal Human Melanocytes Carcinogenesis. Jan, 2008 | Pubmed ID: 17916908 N-acetylcysteine Protects Melanocytes Against Oxidative Stress/damage and Delays Onset of Ultraviolet-induced Melanoma in Mice Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2007 | Pubmed ID: 17908992 Digital Dermoscopic Monitoring of Atypical Nevi in Patients at Risk for Melanoma Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]. Oct, 2007 | Pubmed ID: 17903152 Predominant Formation of Heavily Pigmented Dermal Melanocytomas Resembling 'animal-type' Melanomas in Hepatocyte Growth Factor (C57BL/6 X C3H)F1 Mice Following Neonatal UV Irradiation Journal of Cutaneous Pathology. Sep, 2007 | Pubmed ID: 17696912 Melanocyte Expression of Survivin Promotes Development and Metastasis of UV-induced Melanoma in HGF-transgenic Mice Cancer Research. Jun, 2007 | Pubmed ID: 17545596 Absence of Senescence-associated Beta-galactosidase Activity in Human Melanocytic Nevi in Vivo The Journal of Investigative Dermatology. Oct, 2007 | Pubmed ID: 17522702 Phosphorylation of Mitochondrial Phospholipid Scramblase 3 by Protein Kinase C-delta Induces Its Activation and Facilitates Mitochondrial Targeting of TBid Journal of Cellular Biochemistry. Aug, 2007 | Pubmed ID: 17226776 Proteolytic Cleavage of Livin (ML-IAP) in Apoptotic Melanoma Cells Potentially Mediated by a Non-canonical Caspase Journal of Dermatological Science. Sep, 2006 | Pubmed ID: 16806840 Activation of Dual Apoptotic Pathways in Human Melanocytes and Protection by Survivin The Journal of Investigative Dermatology. Oct, 2006 | Pubmed ID: 16728972 Melanoma Genetics: a Review of Genetic Factors and Clinical Phenotypes in Familial Melanoma Current Opinion in Oncology. Mar, 2006 | Pubmed ID: 16462187 Keratinocyte Apoptosis in Epidermal Development and Disease The Journal of Investigative Dermatology. Feb, 2006 | Pubmed ID: 16418733 Nevus Distribution in a Utah Melanoma Kindred with a Temperature-sensitive CDKN2A Mutation The Journal of Investigative Dermatology. Dec, 2005 | Pubmed ID: 16354203 Proliferation, Apoptosis, and Survivin Expression in a Spectrum of Melanocytic Nevi Journal of Cutaneous Pathology. Jan, 2005 | Pubmed ID: 15660660 Colonization of Adjacent Stem Cell Compartments by Mutant Keratinocytes Seminars in Cancer Biology. Apr, 2005 | Pubmed ID: 15652454 UVB-induced Apoptosis Drives Clonal Expansion During Skin Tumor Development Carcinogenesis. Jan, 2005 | Pubmed ID: 15498793 Imatinib Mesylate for Melanoma: Will a New Target Be Revealed? The Journal of Investigative Dermatology. Dec, 2004 | Pubmed ID: 15610499 Proliferation, Apoptosis, and Survivin Expression in Keratinocytic Neoplasms and Hyperplasias The American Journal of Dermatopathology. Jun, 2004 | Pubmed ID: 15166502 Vulvar Melanoma: Diffuse Melanosis and Metastasis to the Placenta Journal of the American Academy of Dermatology. Feb, 2004 | Pubmed ID: 14726891 Limited Gene Activation in Tumor and Normal Epithelial Cells Treated with the DNA Methyltransferase Inhibitor 5-aza-2'-deoxycytidine Molecular Pharmacology. Jan, 2004 | Pubmed ID: 14722233 Rapid Induction of Mitochondrial Events and Caspase-independent Apoptosis in Survivin-targeted Melanoma Cells Oncogene. Jan, 2004 | Pubmed ID: 14712209 Novel Application of a Fibrin Cell Block Method to Evaluate Melanocytic Cell Populations Pigment Cell Research. Dec, 2003 | Pubmed ID: 14629724 Phospholipid Scramblase 3 Controls Mitochondrial Structure, Function, and Apoptotic Response Molecular Cancer Research : MCR. Oct, 2003 | Pubmed ID: 14573790 Metastatic Melanoma in Pregnancy: Risk of Transplacental Metastases in the Infant Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jun, 2003 | Pubmed ID: 12775744 Survivin Expression in Mouse Skin Prevents Papilloma Regression and Promotes Chemical-induced Tumor Progression Cancer Research. Feb, 2003 | Pubmed ID: 12566297 Apoptosis Regulators and Responses in Human Melanocytic and Keratinocytic Cells The Journal of Investigative Dermatology. Jan, 2003 | Pubmed ID: 12535197 Amifostine Aminothiols and Protection of Keratinocyte Apoptosis and DNA Damage The Journal of Investigative Dermatology. Sep, 2002 | Pubmed ID: 12230519 Transplantasjon av Zebrafish Pediatric Brain Tumors til Immun-kompetente verter for langvarig studie av Tumor Cell Behavior og Drug Response Mattie J. Casey*1, Katarzyna Modzelewska*1, Daniela Anderson1, James Goodman1, Elena F. Boer1, Laura Jimenez1, Douglas Grossman1,2, Rodney A. Stewart1 1Department of Oncological Sciences and Huntsman Cancer Institute, University of Utah School of Medicine, 2Department of Dermatology, University of Utah Health Sciences Center, Salt Lake City JoVE 55712 Cancer Research
Transplantasjon av Zebrafish Pediatric Brain Tumors til Immun-kompetente verter for langvarig studie av Tumor Cell Behavior og Drug Response Mattie J. Casey*1, Katarzyna Modzelewska*1, Daniela Anderson1, James Goodman1, Elena F. Boer1, Laura Jimenez1, Douglas Grossman1,2, Rodney A. Stewart1 1Department of Oncological Sciences and Huntsman Cancer Institute, University of Utah School of Medicine, 2Department of Dermatology, University of Utah Health Sciences Center, Salt Lake City JoVE 55712 Cancer Research
