Graeme F. Woodworth Department of Neurosurgery University of Maryland School of Medicine Biography Publications Institution JoVE Articles Graeme F. Woodworth has not added a biography. If you are Graeme F. Woodworth and would like to personalize this page please email our Author Liaison for assistance. Publications The Roles of Thermal and Mechanical Stress in Focused Ultrasound-mediated Immunomodulation and Immunotherapy for Central Nervous System Tumors Journal of Neuro-oncology. Apr, 2022 | Pubmed ID: 35235137 Pediatric Glioblastoma: Mechanisms of Immune Evasion and Potential Therapeutic Opportunities Cancer Immunology, Immunotherapy : CII. Jan, 2022 | Pubmed ID: 35020009 Towards Controlled Drug Delivery in Brain Tumors with Microbubble-enhanced Focused Ultrasound Advanced Drug Delivery Reviews. 01, 2022 | Pubmed ID: 34801617 Harnessing Nanomedicine for Enhanced Immunotherapy for Breast Cancer Brain Metastases Drug Delivery and Translational Research. 12, 2021 | Pubmed ID: 34716900 Localized Blood-brain Barrier Opening in Infiltrating Gliomas with MRI-guided Acoustic Emissions-controlled Focused Ultrasound Proceedings of the National Academy of Sciences of the United States of America. 09, 2021 | Pubmed ID: 34504017 Elevated Fibroblast Growth Factor-inducible 14 Expression Transforms Proneural-like Gliomas into More Aggressive and Lethal Brain Cancer Glia. 09, 2021 | Pubmed ID: 33991013 Leveraging the Replication-competent Avian-like Sarcoma Virus/tumor Virus Receptor-A System for Modeling Human Gliomas Glia. 09, 2021 | Pubmed ID: 33638562 Bone Flap Resorption in Pediatric Patients Following Autologous Cranioplasty Operative Neurosurgery (Hagerstown, Md.). 04, 2021 | Pubmed ID: 33469664 A Multi-center Analysis of Single-fraction Versus Hypofractionated Stereotactic Radiosurgery for the Treatment of Brain Metastasis Radiation Oncology (London, England). May, 2020 | Pubmed ID: 32466775 MCT4 Regulates De Novo Pyrimidine Biosynthesis in GBM in a Lactate-independent Manner Neuro-oncology Advances. Jan-Dec, 2020 | Pubmed ID: 32002519 Decreased Nonspecific Adhesivity, Receptor-targeted Therapeutic Nanoparticles for Primary and Metastatic Breast Cancer Science Advances. 01, 2020 | Pubmed ID: 31998833 Predictors and Limitations of the Penetration Depth of Photodynamic Effects in the Rodent Brain Photochemistry and Photobiology. 03, 2020 | Pubmed ID: 31441057 Radiosensitization of High-grade Gliomas Through Induced Hyperthermia: Review of Clinical Experience and the Potential Role of MR-guided Focused Ultrasound Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. 01, 2020 | Pubmed ID: 31431370 Systematic Evaluation of Light-Activatable Biohybrids for Anti-Glioma Photodynamic Therapy Journal of Clinical Medicine. Aug, 2019 | Pubmed ID: 31438568 Leveraging Surface Plasmon Resonance to Dissect the Interfacial Properties of Nanoparticles: Implications for Tissue Binding and Tumor Penetration Nanomedicine : Nanotechnology, Biology, and Medicine. 08, 2019 | Pubmed ID: 31176045 Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma Frontiers in Oncology. 2018 | Pubmed ID: 30406029 Prognostic Models for Patients with Brain Metastases After Stereotactic Radiosurgery with or Without Whole Brain Radiotherapy: a Validation Study Journal of Neuro-oncology. Nov, 2018 | Pubmed ID: 30132164 Oxaliplatin Disrupts Pathological Features of Glioma Cells and Associated Macrophages Independent of Apoptosis Induction Journal of Neuro-oncology. Dec, 2018 | Pubmed ID: 30132163 The TNF Receptor Family Member Fn14 is Highly Expressed in Recurrent Glioblastoma and in GBM Patient-derived Xenografts with Acquired Temozolomide Resistance Neuro-oncology. 09, 2018 | Pubmed ID: 29897522 Differential Expression of the TWEAK Receptor Fn14 in IDH1 Wild-type and Mutant Gliomas Journal of Neuro-oncology. Jun, 2018 | Pubmed ID: 29453678 MR-guided Transcranial Focused Ultrasound Safely Enhances Interstitial Dispersion of Large Polymeric Nanoparticles in the Living Brain PloS One. 2018 | Pubmed ID: 29415084 Cross-species Transcriptional Analysis Reveals Conserved and Host-specific Neoplastic Processes in Mammalian Glioma Scientific Reports. 01, 2018 | Pubmed ID: 29352201 Decreased Non-specific Adhesivity, Receptor Targeted (DART) Nanoparticles Exhibit Improved Dispersion, Cellular Uptake, and Tumor Retention in Invasive Gliomas Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2017 | Pubmed ID: 28887134 Genetically Engineered Rat Gliomas: PDGF-driven Tumor Initiation and Progression in Tv-a Transgenic Rats Recreate Key Features of Human Brain Cancer PloS One. 2017 | Pubmed ID: 28358926 Tumor-targeted Nanotherapeutics: Overcoming Treatment Barriers for Glioblastoma Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. Nov, 2016 | Pubmed ID: 27813323 Repurposing Platinum-based Chemotherapies for Multi-modal Treatment of Glioblastoma Oncoimmunology. 2016 | Pubmed ID: 27757301 Emerging Applications of Therapeutic Ultrasound in Neuro-oncology: Moving Beyond Tumor Ablation Neurosurgery. Nov, 2016 | Pubmed ID: 27552589 Non-specific Binding and Steric Hindrance Thresholds for Penetration of Particulate Drug Carriers Within Tumor Tissue Journal of Controlled Release : Official Journal of the Controlled Release Society. Sep, 2016 | Pubmed ID: 27460683 Pulsed Ultrasound Expands the Extracellular and Perivascular Spaces of the Brain Brain Research. Sep, 2016 | Pubmed ID: 27369449 Pathologic Deposition of Non-amyloid Immunoglobulin in the Brain Leading to Mass Effect and Neurological Deficits Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Aug, 2016 | Pubmed ID: 26954763 Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier Current Pharmaceutical Design. 2016 | Pubmed ID: 26685681 The TWEAK Receptor Fn14 is a Potential Cell Surface Portal for Targeted Delivery of Glioblastoma Therapeutics Oncogene. 04, 2016 | Pubmed ID: 26300004 Surface Plasmon Resonance As a High Throughput Method to Evaluate Specific and Non-specific Binding of Nanotherapeutics Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2015 | Pubmed ID: 26415854 Highly PEGylated DNA Nanoparticles Provide Uniform and Widespread Gene Transfer in the Brain Advanced Healthcare Materials. May, 2015 | Pubmed ID: 25761435 Preservation of the Greater Occipital Nerve During Suboccipital Craniectomy Results in a Paradoxical Increase in Postoperative Headaches Neurosurgery. Apr, 2015 | Pubmed ID: 25599212 Minimizing the Non-specific Binding of Nanoparticles to the Brain Enables Active Targeting of Fn14-positive Glioblastoma Cells Biomaterials. Feb, 2015 | Pubmed ID: 25542792 Highly Compacted PH-responsive DNA Nanoparticles Mediate Transgene Silencing in Experimental Glioma Journal of Materials Chemistry. B, Materials for Biology and Medicine. Dec, 2014 | Pubmed ID: 25485114 Emerging Insights into Barriers to Effective Brain Tumor Therapeutics Frontiers in Oncology. 2014 | Pubmed ID: 25101239 Surgical Outcomes Using a Medial-to-lateral Endonasal Endoscopic Approach to Pituitary Adenomas Invading the Cavernous Sinus Journal of Neurosurgery. May, 2014 | Pubmed ID: 24527820 Histopathological Correlates with Survival in Reoperated Glioblastomas Journal of Neuro-oncology. Jul, 2013 | Pubmed ID: 23666202 Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection Safwan Alomari1, Jayanidhi Kedda1, Adarsha P. Malla2,3, Victor Pacis1, Pavlos Anastasiadis2,3, Su Xu4, Emylee McFarland2,3, Lilia Sukhon1, Bruno Gallo5, Jordina Rincon-Torroella1, Netanel Ben-Shalom1, Heather M. Ames3,6, Henry Brem1,7, Graeme F. Woodworth2,3, Betty Tyler1 1Department of Neurosurgery, Johns Hopkins University School of Medicine, 2Department of Neurosurgery, University of Maryland School of Medicine, 3Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, 4Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 5Pontifical Catholic University of Parana, 6Department of Pathology, University of Maryland School of Medicine, 7Departments of Ophthalmology, Oncology and Biomedical Engineering, Johns Hopkins University School of Medicine JoVE 64048 Cancer Research
Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection Safwan Alomari1, Jayanidhi Kedda1, Adarsha P. Malla2,3, Victor Pacis1, Pavlos Anastasiadis2,3, Su Xu4, Emylee McFarland2,3, Lilia Sukhon1, Bruno Gallo5, Jordina Rincon-Torroella1, Netanel Ben-Shalom1, Heather M. Ames3,6, Henry Brem1,7, Graeme F. Woodworth2,3, Betty Tyler1 1Department of Neurosurgery, Johns Hopkins University School of Medicine, 2Department of Neurosurgery, University of Maryland School of Medicine, 3Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, 4Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 5Pontifical Catholic University of Parana, 6Department of Pathology, University of Maryland School of Medicine, 7Departments of Ophthalmology, Oncology and Biomedical Engineering, Johns Hopkins University School of Medicine JoVE 64048 Cancer Research