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Articles by Hugo A. Katus in JoVE
A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology Christian Erbel*1, Deniz Okuyucu*1, Mohammadreza Akhavanpoor1, Li Zhao1, Susanne Wangler1, Maani Hakimi2, Andreas Doesch1, Thomas J. Dengler3, Hugo A. Katus1, Christian A. Gleissner1 1Department of Cardiology, University of Heidelberg, 2Department of Vascular Surgery, University of Heidelberg, 3Department of Cardiology, SLK Hospital am Plattenwald Atherosclerosis is a chronic inflammatory process. This manuscript illustrates an easy to use ex vivo model to investigate fresh carotid or coronary artery plaques. The ex vivo model allows for the investigation of potential substances on the inflammatory milieu in human atherosclerotic lesions and results can be analyzed by various methods.