Ivan Merelli

Publications

• Longitudinal Single-cell Profiling of Chemotherapy Response in Acute Myeloid Leukemia
  Nature Communications. Mar, 2023  |   Pubmed ID: 36890137
• Protocol to Differentiate Monolayer Human Induced Pluripotent Stem Cells into Inflammatory Responsive Astrocytes
  STAR Protocols. Mar, 2023  |   Pubmed ID: 36881505
• Myelomonocytic Cells in Giant Cell Arteritis Activate Trained Immunity Programs Sustaining Inflammation and Cytokine Production
  Rheumatology (Oxford, England). Feb, 2023  |   Pubmed ID: 36802235
• Mesenchymal Stromal Cells Improve the Transplantation Outcome of CRISPR-Cas9 Gene-edited Human HSPCs
  Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2023  |   Pubmed ID: 35982622
• Case Report: Consistent Disease Manifestations with a Staggered Time Course in Two Identical Twins Affected by Adenosine Deaminase 2 Deficiency
  Frontiers in Immunology. 2022  |   Pubmed ID: 36248833
• Choice of Template Delivery Mitigates the Genotoxic Risk and Adverse Impact of Editing in Human Hematopoietic Stem Cells
  Cell Stem Cell. Oct, 2022  |   Pubmed ID: 36206730
• Targeted Inducible Delivery of Immunoactivating Cytokines Reprograms Glioblastoma Microenvironment and Inhibits Growth in Mouse Models
  Science Translational Medicine. Jul, 2022  |   Pubmed ID: 35857642
• Follicular Helper T Cell Signature of Replicative Exhaustion, Apoptosis, and Senescence in Common Variable Immunodeficiency
  European Journal of Immunology. Jul, 2022  |   Pubmed ID: 35562849
• Identification of a Retinoic Acid-dependent Haemogenic Endothelial Progenitor from Human Pluripotent Stem Cells
  Nature Cell Biology. May, 2022  |   Pubmed ID: 35484246
• Integrated Multiomic Profiling Identifies the Epigenetic Regulator PRC2 As a Therapeutic Target to Counteract Leukemia Immune Escape and Relapse
  Cancer Discovery. Jun, 2022  |   Pubmed ID: 35255120
• Myeloid Cell-based Delivery of IFN-γ Reprograms the Leukemia Microenvironment and Induces Anti-tumoral Immune Responses
  EMBO Molecular Medicine. Oct, 2021  |   Pubmed ID: 34459560
• Oncogene-induced Senescence in Hematopoietic Progenitors Features Myeloid Restricted Hematopoiesis, Chronic Inflammation and Histiocytosis
  Nature Communications. Jul, 2021  |   Pubmed ID: 34315896
• Premature Senescence and Increased Oxidative Stress in the Thymus of Down Syndrome Patients
  Frontiers in Immunology. 2021  |   Pubmed ID: 34140950
• Oncogene-induced Maladaptive Activation of Trained Immunity in the Pathogenesis and Treatment of Erdheim-Chester Disease
  Blood. Oct, 2021  |   Pubmed ID: 34077954
• BAR-Seq Clonal Tracking of Gene-edited Cells
  Nature Protocols. Jun, 2021  |   Pubmed ID: 34031609
• Modeling, Optimization, and Comparable Efficacy of T Cell and Hematopoietic Stem Cell Gene Editing for Treating Hyper-IgM Syndrome
  EMBO Molecular Medicine. Mar, 2021  |   Pubmed ID: 33475257
• Expanded Circulating Hematopoietic Stem/progenitor Cells As Novel Cell Source for the Treatment of TCIRG1 Osteopetrosis
  Haematologica. Jan, 2021  |   Pubmed ID: 31949009
• Efficient Gene Editing of Human Long-term Hematopoietic Stem Cells Validated by Clonal Tracking
  Nature Biotechnology. Nov, 2020  |   Pubmed ID: 32601433
• Hematopoietic Stem Cell Function in β-thalassemia is Impaired and is Rescued by Targeting the Bone Marrow Niche
  Blood. Jul, 2020  |   Pubmed ID: 32344432
• γ-TRIS: a Graph-algorithm for Comprehensive Identification of Vector Genomic Insertion Sites
  Bioinformatics (Oxford, England). Mar, 2020  |   Pubmed ID: 31589304
• Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient P53-Mediated DNA Damage Response
  Cell Stem Cell. Apr, 2019  |   Pubmed ID: 30905619
• High Parathyroid Hormone Concentration in Tenofovir-treated Patients Are Due to Inhibition of Calcium-sensing Receptor Activity
  Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Jan, 2018  |   Pubmed ID: 29136775