Jacco van Rheenen Department of Molecular Pathology The Netherlands Cancer Institute Biography Publications Institution JoVE Articles Jacco van Rheenen has not added a biography. If you are Jacco van Rheenen and would like to personalize this page please email our Author Liaison for assistance. Publications A Living Biobank of Patient-derived Ductal Carcinoma in Situ Mouse-intraductal Xenografts Identifies Risk Factors for Invasive Progression Cancer Cell. May, 2023 | Pubmed ID: 37116492 A Lamb1Dendra2 Mouse Model Identifies Basement-membrane-producing Origins and Dynamics in PyMT Breast Tumors Developmental Cell. Apr, 2023 | Pubmed ID: 36905927 Subtype-specific Kinase Dependency Regulates Growth and Metastasis of Poor-prognosis Mesenchymal Colorectal Cancer Journal of Experimental & Clinical Cancer Research : CR. Mar, 2023 | Pubmed ID: 36869386 Author Correction: Epithelial TGFβ Engages Growth-factor Signalling to Circumvent Apoptosis and Drive Intestinal Tumourigenesis with Aggressive Features Nature Communications. Jan, 2023 | Pubmed ID: 36720858 Coordinated Cancer Chaos Cell. Jan, 2023 | Pubmed ID: 36669470 Multidimensional Imaging of Breast Cancer Cold Spring Harbor Perspectives in Medicine. May, 2023 | Pubmed ID: 36167726 Epithelial TGFβ Engages Growth-factor Signalling to Circumvent Apoptosis and Drive Intestinal Tumourigenesis with Aggressive Features Nature Communications. Dec, 2022 | Pubmed ID: 36477656 Re-purposing the Pro-senescence Properties of Doxorubicin to Introduce Immunotherapy in Breast Cancer Brain Metastasis Cell Reports. Medicine. Nov, 2022 | Pubmed ID: 36384097 A Doxycycline- and Light-inducible Cre Recombinase Mouse Model for Optogenetic Genome Editing Nature Communications. Oct, 2022 | Pubmed ID: 36307419 Author Correction: PHGDH Heterogeneity Potentiates Cancer Cell Dissemination and Metastasis Nature. Sep, 2022 | Pubmed ID: 36042336 Retrograde Movements Determine Effective Stem Cell Numbers in the Intestine Nature. Jul, 2022 | Pubmed ID: 35831497 Epithelial-to-Mesenchymal Transition Drives Invasiveness of Breast Cancer Brain Metastases Cancers. Jun, 2022 | Pubmed ID: 35804890 PHGDH Heterogeneity Potentiates Cancer cell Dissemination and Metastasis Nature. May, 2022 | Pubmed ID: 35585241 GFAP Splice Variants Fine-tune Glioma Cell Invasion and Tumour Dynamics by Modulating Migration Persistence Scientific Reports. Jan, 2022 | Pubmed ID: 35013418 Differential Survival and Therapy Benefit of Breast Cancer Patients Are Characterized by Distinct Epithelial and Immune Cell Microenvironments Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2021 | Pubmed ID: 34965952 Regulation of a Progenitor Gene Program by SOX4 is Essential for Mammary Tumor Proliferation Oncogene. Nov, 2021 | Pubmed ID: 34584219 RASSF1C Oncogene Elicits Amoeboid Invasion, Cancer Stemness, and Extracellular Vesicle Release Via a SRC/Rho Axis The EMBO Journal. Oct, 2021 | Pubmed ID: 34532864 Single-cell Analysis of Regions of Interest (SCARI) Using a Photosensitive Tag Nature Chemical Biology. Nov, 2021 | Pubmed ID: 34504322 Diverse Transcriptional Regulation and Functional Effects Revealed by CRISPR/Cas9-directed Epigenetic Editing Oncotarget. Aug, 2021 | Pubmed ID: 34434494 Epithelial-to-Mesenchymal Transition in the Light of Plasticity and Hybrid E/M States Journal of Clinical Medicine. May, 2021 | Pubmed ID: 34072345 LGR6 Marks Nephron Progenitor Cells Developmental Dynamics : an Official Publication of the American Association of Anatomists. Apr, 2021 | Pubmed ID: 33848015 Resistance of Hypoxic Cells to Ionizing Radiation Is Mediated in Part Via Hypoxia-Induced Quiescence Cells. Mar, 2021 | Pubmed ID: 33801903 A Comprehensive Enhancer Screen Identifies TRAM2 As a Key and Novel Mediator of YAP Oncogenesis Genome Biology. Jan, 2021 | Pubmed ID: 33514403 Scratch-induced Partial Skin Wounds Re-epithelialize by Sheets of Independently Migrating Keratinocytes Life Science Alliance. 01, 2021 | Pubmed ID: 33257474 Targeting Dormant Tumor Cells to Prevent Cancer Recurrence The FEBS Journal. Nov, 2021 | Pubmed ID: 33190412 Publisher Correction: Long-distance Modulation of Bystander Tumor Cells by CD8 T-cell-secreted IFN-γ Nature Cancer. Jul, 2020 | Pubmed ID: 35122043 An Unanticipated Tumor-suppressive Role of the SUMO Pathway in the Intestine Unveiled by Ubc9 Haploinsufficiency Oncogene. Oct, 2020 | Pubmed ID: 32948837 Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine Cell Reports. 07, 2020 | Pubmed ID: 32698002 Stem Cell Lineage Survival As a Noisy Competition for Niche Access Proceedings of the National Academy of Sciences of the United States of America. 07, 2020 | Pubmed ID: 32611816 Long-distance Modulation of Bystander Tumor Cells by CD8 T Cell-secreted IFNγ Nature Cancer. Mar, 2020 | Pubmed ID: 32566933 Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer Cell Stem Cell. 04, 2020 | Pubmed ID: 32169167 Poor Perfusion of the Microvasculature in Peritoneal Metastases of Ovarian Cancer Clinical & Experimental Metastasis. Apr, 2020 | Pubmed ID: 32008138 Capturing Stem Cell Behavior Using Intravital and Live Cell Microscopy Cold Spring Harbor Perspectives in Biology. Sep, 2020 | Pubmed ID: 31767651 Cellular Plasticity During Metastasis: New Insights Provided by Intravital Microscopy Cold Spring Harbor Perspectives in Medicine. Nov, 2020 | Pubmed ID: 31615867 Fsp1-Mediated Lineage Tracing Fails to Detect the Majority of Disseminating Cells Undergoing EMT Cell Reports. 11, 2019 | Pubmed ID: 31775027 Rebalancing of Actomyosin Contractility Enables Mammary Tumor Formation Upon Loss of E-cadherin Nature Communications. Aug, 2019 | Pubmed ID: 31444332 Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids Cell Stem Cell. Jun, 2019 | Pubmed ID: 31130514 Cancer Cells Copy Migratory Behavior and Exchange Signaling Networks Via Extracellular Vesicles The EMBO Journal. 08, 2018 | Pubmed ID: 29907695 Glycosylated Extracellular Vesicles Released by Glioblastoma Cells Are Decorated by CCL18 Allowing for Cellular Uptake Via Chemokine Receptor CCR8 Journal of Extracellular Vesicles. 2018 | Pubmed ID: 29696074 A Surgical Orthotopic Organoid Transplantation Approach in Mice to Visualize and Study Colorectal Cancer Progression Nature Protocols. 02, 2018 | Pubmed ID: 29300390 Intravital Characterization of Tumor Cell Migration in Pancreatic Cancer Intravital. 2016 | Pubmed ID: 28243522 A Vulnerability of a Subset of Colon Cancers with Potential Clinical Utility Cell. Apr, 2016 | Pubmed ID: 27058664 Intravital FRET Imaging of Tumor Cell Viability and Mitosis During Chemotherapy PloS One. 2013 | Pubmed ID: 23691140 Tissue-resident Memory CD8+ T Cells Continuously Patrol Skin Epithelia to Quickly Recognize Local Antigen Proceedings of the National Academy of Sciences of the United States of America. Nov, 2012 | Pubmed ID: 23150545 죽음 수용 체 CD95 Cofilin 통로를 자극 하는 종양 세포 침공을 활성화 합니다 EMBO Reports. Sep, 2011 | Pubmed ID: 21760611 Intravital 현미경 검사 법: 종양의 전이에 대 한 새로운 통찰력 Journal of Cell Science. Feb, 2011 | Pubmed ID: 21242309 장 토 굴 항상성 대칭 Lgr5 줄기 세포 분열 사이의 중립 경쟁에서 유래한 다 Cell. Oct, 2010 | Pubmed ID: 20887898 막 지형 나노 이미징 세포 생물학의 해석을 영향을 줍니다 Nature Methods. Jul, 2010 | Pubmed ID: 20588265 Phosphatidylinositol-4, 5-bisphosphate-cofilin 상호 Unbalancing 손상 셀 스티어링 Molecular Biology of the Cell. Nov, 2009 | Pubmed ID: 19741095 Cortactin Cofilin 및 Invadopodium 어셈블리와 성숙의 단계를 제어 하려면 N-말 벌 활동을 조절 The Journal of Cell Biology. Aug, 2009 | Pubmed ID: 19704022 셀 콜라겐 기반 마이그레이션 모델 생체 외 및 생체 조건 Seminars in Cell & Developmental Biology. Oct, 2009 | Pubmed ID: 19682592 침 윤 성 종양 세포와 염증 세포의 일반적인 Cofilin 활동 주기 Journal of Cell Science. Feb, 2009 | Pubmed ID: 19158339 유 방 영상 창을 통해 전이성 동작 Intravital 이미징 Nature Methods. Dec, 2008 | Pubmed ID: 18997781 MRP 지역화 조절 메커니즘에 대 한 조사입니다 Experimental Cell Research. Jan, 2008 | Pubmed ID: 17897642 EGF 유도 PIP2 가수분해를 해제 하 고 Cofilin 암 세포에서 로컬로 활성화 됩니다 The Journal of Cell Biology. Dec, 2007 | Pubmed ID: 18086920 떠들고 인 산화 Integrin Beta4 소 단위의 상피 성장 인자 수용 체 유도 Hemidesmosome 중단 필요 하다 Molecular Biology of the Cell. Sep, 2007 | Pubmed ID: 17615294 세포의 운동 성 및 침입과 전이에서 Cytoskeletal 규제 Journal of Mammary Gland Biology and Neoplasia. Sep, 2007 | Pubmed ID: 17557195 형광 표식 및 무서 워 Intravital 이미징 프로브 DNA 문신에 의해 제공 합니다 BMC Biotechnology. 2007 | Pubmed ID: 17201912 스트레스 유발 Apoptosis 조절에 PtdIns (4, 5) P 2와 Pip5kalpha에 대 한 역할 Current Biology : CB. Sep, 2006 | Pubmed ID: 16979564 Integrin 바위와 상호 작용 하는 세포질 도메인 관련 단백질-1 (ICAP-1)-나 플라즈마 멤브레인에 니 Journal of Cellular Physiology. Sep, 2006 | Pubmed ID: 16741948 Integrins Rho Cofilin 통로 통해 운동 전략을 제어합니다 The Journal of Cell Biology. May, 2005 | Pubmed ID: 15866889 PIP2 지질 도메인에서 신호: 중요 한 재평가 The EMBO Journal. May, 2005 | Pubmed ID: 15861130 MIIC와 Phagosome을 이용한 면역 탈출 내 HLA-DM/HLA-DR 상호 작용의 공간 분리 Immunity. Feb, 2005 | Pubmed ID: 15723810 Confocal 수집 민감하게 방출 하 여 형광 공명 에너지 전달의 이미지를 최적화 하기 위해 수정 합니다 Biophysical Journal. Apr, 2004 | Pubmed ID: 15041688 길 항 제를 이용한 PIP(2) 가수분해 억제 대뇌 피 질의 말라 역학: 규제는 글로벌에서 아니라 마이크로 미터 규모에 Molecular Biology of the Cell. Sep, 2002 | Pubmed ID: 12221130 장 리모델링을 연구하기 위한 레이저 절제 및 생체 내 현미경 검사 Dimitrios Laskaris*1,2, Maria Azkanaz*1,2, Mijke A. de Vreij-Kruidenier3, Doreen van Rijswoud-Ram3, Hendrik A. Messal1,2, Jacco van Rheenen1,2 1Department of Molecular Pathology, The Netherlands Cancer Institute, 2Oncode Institute, 3Animal Laboratory Facility, The Netherlands Cancer Institute JoVE 64756 Biology 교체 가능한 뚜껑이있는 유방 이미징 창을 사용하는 종방향 생체 내 현미경 검사 Larissa Mourao1,2, Marta Ciwinska1,2, Jacco van Rheenen3, Colinda L. G. J. Scheele1,2 1Center for Cancer Biology, VIB (BE), 2Department of Oncology, KU Leuven (BE), 3Netherlands Cancer Institute, Department of Molecular Pathology, Oncode Institute (NL) JoVE 63326 Biology 내유 이미징 창문 Dendra2 Photoswitching Bojana Gligorijevic1,2, Dmitriy Kedrin1, Jeffrey E Segall1, John Condeelis1,2, Jacco van Rheenen1,2,3 1Department of Anatomy and Structural Biology, Albert Einstein College of Medicine - Yeshiva University, 2Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine - Yeshiva University, 3Hubrecht Institute-KNAW and University Medical Center Utrecht JoVE 1278 Biology
장 리모델링을 연구하기 위한 레이저 절제 및 생체 내 현미경 검사 Dimitrios Laskaris*1,2, Maria Azkanaz*1,2, Mijke A. de Vreij-Kruidenier3, Doreen van Rijswoud-Ram3, Hendrik A. Messal1,2, Jacco van Rheenen1,2 1Department of Molecular Pathology, The Netherlands Cancer Institute, 2Oncode Institute, 3Animal Laboratory Facility, The Netherlands Cancer Institute JoVE 64756 Biology
교체 가능한 뚜껑이있는 유방 이미징 창을 사용하는 종방향 생체 내 현미경 검사 Larissa Mourao1,2, Marta Ciwinska1,2, Jacco van Rheenen3, Colinda L. G. J. Scheele1,2 1Center for Cancer Biology, VIB (BE), 2Department of Oncology, KU Leuven (BE), 3Netherlands Cancer Institute, Department of Molecular Pathology, Oncode Institute (NL) JoVE 63326 Biology
내유 이미징 창문 Dendra2 Photoswitching Bojana Gligorijevic1,2, Dmitriy Kedrin1, Jeffrey E Segall1, John Condeelis1,2, Jacco van Rheenen1,2,3 1Department of Anatomy and Structural Biology, Albert Einstein College of Medicine - Yeshiva University, 2Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine - Yeshiva University, 3Hubrecht Institute-KNAW and University Medical Center Utrecht JoVE 1278 Biology