Jiasheng Zhang Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine Yale University School of Medicine Biography Publications Institution JoVE Articles Jiasheng Zhang has not added a biography. If you are Jiasheng Zhang and would like to personalize this page please email our Author Liaison for assistance. Publications VE-Cadherin Phosphorylation Regulates Endothelial Fluid Shear Stress Responses Through the Polarity Protein LGN Current Biology : CB. Jul, 2017 | Pubmed ID: 28712573 PKN1 Directs Polarized RAB21 Vesicle Trafficking Via RPH3A and Is Important for Neutrophil Adhesion and Ischemia-Reperfusion Injury Cell Reports. Jun, 2017 | Pubmed ID: 28636945 FGF-dependent Metabolic Control of Vascular Development Nature. 05, 2017 | Pubmed ID: 28467822 Preclinical Evaluation of RYM1, a Matrix Metalloproteinase-Targeted Tracer for Imaging Aneurysm Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Aug, 2017 | Pubmed ID: 28360209 Matrix Metalloproteinase-Targeted Imaging of Lung Inflammation and Remodeling Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jan, 2017 | Pubmed ID: 27469361 Optical Imaging of MMP-12 Active Form in Inflammation and Aneurysm Scientific Reports. Dec, 2016 | Pubmed ID: 27917892 The Robo4 Cytoplasmic Domain is Dispensable for Vascular Permeability and Neovascularization Nature Communications. Nov, 2016 | Pubmed ID: 27882935 Syndecan 4 Controls Lymphatic Vasculature Remodeling During Mouse Embryonic Development Development (Cambridge, England). Dec, 2016 | Pubmed ID: 27789626 Matrix Metalloproteinase Inhibitor, Doxycycline and Progression of Calcific Aortic Valve Disease in Hyperlipidemic Mice Scientific Reports. Sep, 2016 | Pubmed ID: 27619752 Engineered Tissue-Stent Biocomposites As Tracheal Replacements Tissue Engineering. Part A. Sep, 2016 | Pubmed ID: 27520928 Iron Catalysis for Room-Temperature Aerobic Oxidation of Alcohols to Carboxylic Acids Journal of the American Chemical Society. Jul, 2016 | Pubmed ID: 27304226 Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia Via Complement Activation Cell. May, 2016 | Pubmed ID: 27114033 The Neuropilin-like Protein ESDN Regulates Insulin Signaling and Sensitivity American Journal of Physiology. Heart and Circulatory Physiology. May, 2016 | Pubmed ID: 26921437 MiR-182 Modulates Myocardial Hypertrophic Response Induced by Angiogenesis in Heart Scientific Reports. Feb, 2016 | Pubmed ID: 26888314 Integrin β3 Inhibition is a Therapeutic Strategy for Supravalvular Aortic Stenosis The Journal of Experimental Medicine. Mar, 2016 | Pubmed ID: 26858344 Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neovascularization Circulation. Jan, 2016 | Pubmed ID: 26659946 Impaired LRP6-TCF7L2 Activity Enhances Smooth Muscle Cell Plasticity and Causes Coronary Artery Disease Cell Reports. Oct, 2015 | Pubmed ID: 26489464 Interferon-γ-mediated Allograft Rejection Exacerbates Cardiovascular Disease of Hyperlipidemic Murine Transplant Recipients Circulation Research. Nov, 2015 | Pubmed ID: 26399469 Multimodality and Molecular Imaging of Matrix Metalloproteinase Activation in Calcific Aortic Valve Disease Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jun, 2015 | Pubmed ID: 25908827 General CuBr2-catalyzed Highly Enantioselective Approach for Optically Active Allenols from Terminal Alkynols Chemical Communications (Cambridge, England). Apr, 2015 | Pubmed ID: 25797036 Harmony of CdI2 with CuBr for the One-pot Synthesis of Optically Active α-allenols Organic & Biomolecular Chemistry. Apr, 2015 | Pubmed ID: 25740403 Imaging Vessel Wall Biology to Predict Outcome in Abdominal Aortic Aneurysm Circulation. Cardiovascular Imaging. Jan, 2015 | Pubmed ID: 25550400 ELAVL1 Regulates Alternative Splicing of EIF4E Transporter to Promote Postnatal Angiogenesis Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25422430 Loss of Mitochondrial Fission Depletes Axonal Mitochondria in Midbrain Dopamine Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2014 | Pubmed ID: 25339743 Chemokine-coupled β2 Integrin-induced Macrophage Rac2-Myosin IIA Interaction Regulates VEGF-A MRNA Stability and Arteriogenesis The Journal of Experimental Medicine. Sep, 2014 | Pubmed ID: 25180062 The Vestigial Enzyme D-dopachrome Tautomerase Protects the Heart Against Ischemic Injury The Journal of Clinical Investigation. Aug, 2014 | Pubmed ID: 24983315 PTP1b is a Physiologic Regulator of Vascular Endothelial Growth Factor Signaling in Endothelial Cells Circulation. Sep, 2014 | Pubmed ID: 24982127 Netrin-1 Controls Sympathetic Arterial Innervation The Journal of Clinical Investigation. Jul, 2014 | Pubmed ID: 24937433 A Correlation Study of the Expression of Resistin and Glycometabolism in Muscle Tissue After Traumatic Brain Injury in Rats Chinese Journal of Traumatology = Zhonghua Chuang Shang Za Zhi. 2014 | Pubmed ID: 24889973 CCR2 Deficiency Impairs Macrophage Infiltration and Improves Cognitive Function After Traumatic Brain Injury Journal of Neurotrauma. Oct, 2014 | Pubmed ID: 24806994 Enantioselective Double Manipulation of Tetrahydroisoquinolines with Terminal Alkynes and Aldehydes Under Copper(I) Catalysis Angewandte Chemie (International Ed. in English). Jan, 2014 | Pubmed ID: 24375740 Lipid Lowering and Imaging Protease Activation in Atherosclerosis Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. Apr, 2014 | Pubmed ID: 24368425 Angiopoietin-2 Secretion by Endothelial Cell Exosomes: Regulation by the Phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial Nitric Oxide Synthase (eNOS) and Syndecan-4/syntenin Pathways The Journal of Biological Chemistry. Jan, 2014 | Pubmed ID: 24235146 Transmembrane Protein ESDN Promotes Endothelial VEGF Signaling and Regulates Angiogenesis The Journal of Clinical Investigation. Dec, 2013 | Pubmed ID: 24177422 A Network of Interactions Enables CCM3 and STK24 to Coordinate UNC13D-driven Vesicle Exocytosis in Neutrophils Developmental Cell. Oct, 2013 | Pubmed ID: 24176643 Urocortin 2 Autocrine/paracrine and Pharmacologic Effects to Activate AMP-activated Protein Kinase in the Heart Proceedings of the National Academy of Sciences of the United States of America. Oct, 2013 | Pubmed ID: 24043794 Cadmium Iodide-mediated Allenylation of Terminal Alkynes with Ketones Nature Communications. 2013 | Pubmed ID: 24042852 Endothelial Cell-dependent Regulation of Arteriogenesis Circulation Research. Oct, 2013 | Pubmed ID: 23897694 The Neuropilin 1 Cytoplasmic Domain is Required for VEGF-A-dependent Arteriogenesis Developmental Cell. Apr, 2013 | Pubmed ID: 23639442 Progranulin Deficiency Promotes Neuroinflammation and Neuron Loss Following Toxin-induced Injury The Journal of Clinical Investigation. Nov, 2012 | Pubmed ID: 23041626 Molecular Imaging of Vascular Endothelial Growth Factor Receptors in Graft Arteriosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2012 | Pubmed ID: 22723442 Atherosclerosis Plaque Heterogeneity and Response to Therapy Detected by in Vivo Molecular Imaging of Matrix Metalloproteinase Activation Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Nov, 2011 | Pubmed ID: 21969358 Integrin-targeted Imaging of Inflammation in Vascular Remodeling Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2011 | Pubmed ID: 21940943 Loss of Nuclear Factor E2-related Factor 1 in the Brain Leads to Dysregulation of Proteasome Gene Expression and Neurodegeneration Proceedings of the National Academy of Sciences of the United States of America. May, 2011 | Pubmed ID: 21536885 Matrix Metalloproteinase Activation Predicts Amelioration of Remodeling After Dietary Modification in Injured Arteries Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2011 | Pubmed ID: 20947820 Extensive FUS-immunoreactive Pathology in Juvenile Amyotrophic Lateral Sclerosis with Basophilic Inclusions Brain Pathology (Zurich, Switzerland). Nov, 2010 | Pubmed ID: 20579074 Molecular Imaging of Matrix Metalloproteinase Activation to Predict Murine Aneurysm Expansion in Vivo Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jul, 2010 | Pubmed ID: 20554725 VEGF Blockade Inhibits Lymphocyte Recruitment and Ameliorates Immune-mediated Vascular Remodeling Circulation Research. Aug, 2010 | Pubmed ID: 20538685 Two Genetic Variants of CD38 in Subjects with Autism Spectrum Disorder and Controls Neuroscience Research. Jun, 2010 | Pubmed ID: 20435366 Endothelial and Smooth Muscle-derived Neuropilin-like Protein Regulates Platelet-derived Growth Factor Signaling in Human Vascular Smooth Muscle Cells by Modulating Receptor Ubiquitination The Journal of Biological Chemistry. Oct, 2009 | Pubmed ID: 19696027 Molecular Imaging of Activated Matrix Metalloproteinases in Vascular Remodeling Circulation. Nov, 2008 | Pubmed ID: 18936327 HIPK2 Represses Beta-catenin-mediated Transcription, Epidermal Stem Cell Expansion, and Skin Tumorigenesis Proceedings of the National Academy of Sciences of the United States of America. Aug, 2007 | Pubmed ID: 17666529 Syntheses and Structures of Heterometallic Clusters by the Reaction of O-carboranyl Cobaltadichalcogenolato Complexes Dalton Transactions (Cambridge, England : 2003). Feb, 2007 | Pubmed ID: 17279246 Essential Function of HIPK2 in TGFbeta-dependent Survival of Midbrain Dopamine Neurons Nature Neuroscience. Jan, 2007 | Pubmed ID: 17159989 Synthesis and Characterization of Binuclear Half-sandwich Metal (Co, Ir and Ru) Complexes Containing Ancillary Ortho-carborane-1,2-dithiolato Ligands Dalton Transactions (Cambridge, England : 2003). Nov, 2006 | Pubmed ID: 17088961 Dynamic Expression of Neurotrophic Factor Receptors in Postnatal Spinal Motoneurons and in Mouse Model of ALS Journal of Neurobiology. Jul, 2006 | Pubmed ID: 16680759 Hybrid Positron Detection and Optical Coherence Tomography System: Design, Calibration, and Experimental Validation with Rabbit Atherosclerotic Models Journal of Biomedical Optics. Jul-Aug, 2005 | Pubmed ID: 16178644 Alphavbeta3-targeted Detection of Arteriopathy in Transplanted Human Coronary Arteries: an Autoradiographic Study FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2005 | Pubmed ID: 16150802 Noninvasive Imaging of Angiogenesis with a 99mTc-labeled Peptide Targeted at Alphavbeta3 Integrin After Murine Hindlimb Ischemia Circulation. Jun, 2005 | Pubmed ID: 15956134 TH1 Immune Responses to Fully MHC Mismatched Allografts Are Diminished in the Absence of MyD88, a Toll-like Receptor Signal Adaptor Protein American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Sep, 2004 | Pubmed ID: 15307830 Detection of Injury-induced Vascular Remodeling by Targeting Activated Alphavbeta3 Integrin in Vivo Circulation. Jul, 2004 | Pubmed ID: 15210600 Using In Vivo and Tissue and Cell Explant Approaches to Study the Morphogenesis and Pathogenesis of the Embryonic and Perinatal Aorta Ashish Misra1, Zhonghui Feng1, Jiasheng Zhang1, Zhi-Yin Lou2,3, Daniel M. Greif1 1Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, 2Department of Neurology, Yale University School of Medicine, 3Department of Neurology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine JoVE 56039 Developmental Biology
Using In Vivo and Tissue and Cell Explant Approaches to Study the Morphogenesis and Pathogenesis of the Embryonic and Perinatal Aorta Ashish Misra1, Zhonghui Feng1, Jiasheng Zhang1, Zhi-Yin Lou2,3, Daniel M. Greif1 1Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, 2Department of Neurology, Yale University School of Medicine, 3Department of Neurology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine JoVE 56039 Developmental Biology
