Lydia L. Sohn

Mechanical Engineering

University of California, Berkeley

Lydia L. Sohn

Lydia L. Sohn received her A.B. (Chemistry and Physics, 1988), M.S. (Physics, 1990), and Ph.D. (Physics, 1992) from Harvard University. She was an NSF/NATO postdoc at Delft University of Technology and a postdoc at AT&T Bell Laboratories (1993-1995). Sohn was an Assistant Professor of Physics at Princeton University prior to joining the Mechanical Engineering Dept. at UC Berkeley in 2003. In addition to being Professor of Mechanical Engineering, Sohn is a core-member of the UC San Francisco-UC Berkeley Graduate Program in Bioengineering and is currently serving as a member of the program's Executive Committee . Her work focuses on developing quantitative techniques to probe single cells, as they relate to cancer and stem cells. Sohn has received numerous awards including the NSF CAREER, Army of Research Young Investigator Award, DuPont Young Professor Award, and a Bakar Fellowship. In 2010, Sohn received the prestigious W. M. Keck Foundation Medical Research award to develop a label-free method for screening and sorting rare cells. In 2014, Sohn’s developed label-free method—Node-Pore Sensing (NPS)—was named one of five “Revolutionary Platform Technologies for Advancing Life Sciences Research” in a competition sponsored by 6 major foundations, including the W. M. Keck Foundation, Gordon & Betty Moore Foundation, Kavli Foundation, Burroughs-Wellcome Fund, John Templeton Foundation, and Research Corporation. She is a Fellow of the American Institute for Medical and Biological Engineering and a Chancellor's Professor at UC Berkeley.


Patterning the Geometry of Human Embryonic Stem Cell Colonies on Compliant Substrates to Control Tissue-Level Mechanics

1Graduate Program in Bioengineering, University of California San Francisco and University of California Berkeley, 2Center for Bioengineering and Tissue Regeneration, Department of Surgery, University of California San Francisco, 3Department of Mechanical Engineering, University of California Berkeley, 4Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, 5UCSF Comprehensive Cancer Center, Helen Diller Family Cancer Research Center, University of California San Francisco, 6Department of Anatomy, Department of Bioengineering and Therapeutic Sciences, and Department of Radiation Oncology, University of California San Francisco

JoVE 60334