Matthew Daniels

Faculty of Medicine, Biology & Health

University of Manchester

Matthew Daniels

I am a practicing academic cardiologist currently employed at the Senior Lecturer (Associate Professor equivalent) by Manchester University and Manchester Universities NHS hospital trust.

I was previously supported by the Wellcome Trust as a Clinical Intermediate fellow and honorary consultant, and based in the University of Oxford for a decade (2008-19).

I completed a decade in Cambridge University as an MB/PhD student rising ultimately to University Clinical Lecturer in Medicine (1997-2008).

My weekly clinical practice includes inherited cardiac and adult congenital clinics. I provide the PFO closure service for the North West, and have research interests in various aspects of structrual heart disease (TAVR, LAAC, PFOc, PVL), the genetics and genomics of inherited cardiac conditions and development of basic science technologies to enable cardiac repair and cardiac drug testing using stem cell derived platforms. A central focus of this has been development and application of live cell imaging approaches enabled by genetically encoded fluorescent protein technology to cardiomyoctes to directly visualise how they work in health and disease.

I led the Emerging Leader program for the largest cardiac interventional society in the world (SCAI); am a member of the British Cardiac Society Programme Committee, and a member of the Association of Inherited Cardiac Conditions.

Publications

High-Throughput Optical Controlling and Recording Calcium Signal in iPSC-Derived Cardiomyocytes for Toxicity Testing and Phenotypic Drug Screening

1LumiSTAR Biotechnology, Inc., 2NEXEL Co., Ltd., 3Institute of Pharmacology, College of Medicine, National Taiwan University, 4Manchester Heart Centre, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, 5Division of Cardiovascular Sciences, Manchester Academic Health Sciences Centre, University of Manchester, 6Division of Cell Matrix Biology and Regenerative Medicine, University of Manchester

JoVE 63175

 Medicine