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Articles by Miriam Tannenbaum in JoVE
Mapping Genome-wide Accessible Chromatin in Primary Human T Lymphocytes by ATAC-Seq Ivana Grbesa1, Miriam Tannenbaum1, Avital Sarusi-Portuguez1, Michal Schwartz1, Ofir Hakim1 1The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University Assay for Transposase-Accessible Chromatin coupled with high-throughput sequencing (ATAC-seq) is a genome-wide method to uncover accessible chromatin. This is a step-by-step ATAC-seq protocol, from molecular to the final computational analysis, optimized for human lymphocytes (Th1/Th2). This protocol can be adopted by researchers without prior experience in next-generation sequencing methods.