Piero Marchetti Department of Endocrinology and Metabolism Metabolic Unit University of Pisa Biography Publications Institution JoVE Articles Piero Marchetti has not added a biography. If you are Piero Marchetti and would like to personalize this page please email our Author Liaison for assistance. Publications Follow-up of Secondary Diabetic Complications After Pancreas Transplantation Current Opinion in Organ Transplantation. Dec, 2012 | Pubmed ID: 23283247 Central Role and Mechanisms of β-cell Dysfunction and Death in Friedreich Ataxia-associated Diabetes Annals of Neurology. Dec, 2012 | Pubmed ID: 23280845 Microarray Analysis of Isolated Human Islet Transcriptome in Type 2 Diabetes and the Role of the Ubiquitin-proteasome System in Pancreatic Beta Cell Dysfunction Molecular and Cellular Endocrinology. Dec, 2012 | Pubmed ID: 23246353 Ultrastructural Morphometric Analysis of Insulin Secretory Granules in Human Type 2 Diabetes Acta Diabetologica. Dec, 2012 | Pubmed ID: 23184237 From Genotype to Human β Cell Phenotype and Beyond Islets. Sep, 2012 | Pubmed ID: 23073174 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy Autophagy. Apr, 2012 | Pubmed ID: 22966490 Transplantation of the Pancreas Current Diabetes Reports. Oct, 2012 | Pubmed ID: 22828824 Death Protein 5 and P53-upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress-mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-cell Apoptosis Diabetes. Nov, 2012 | Pubmed ID: 22773666 ECTOPIC EXPRESSION OF FSH RECEPTOR ISOFORMS IN NEOPLASTIC BUT NOT IN ENDOTHELIAL CELLS FROM PANCREATIC NEUROENDOCRINE TUMOURS Journal of Endocrinological Investigation. Jun, 2012 | Pubmed ID: 22732316 Nanomedicine for Treatment of Diabetes in an Aging Population: State-of-the-art and Future Developments Nanomedicine : Nanotechnology, Biology, and Medicine. Sep, 2012 | Pubmed ID: 22640905 Age- and Diet-dependent Requirement of DJ-1 for Glucose Homeostasis in Mice with Implications for Human Type 2 Diabetes Journal of Molecular Cell Biology. Aug, 2012 | Pubmed ID: 22611253 Palmitate Activates Autophagy in INS-1E β-cells and in Isolated Rat and Human Pancreatic Islets PloS One. 2012 | Pubmed ID: 22563482 The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-inflammatory Cytokines PLoS Genetics. 2012 | Pubmed ID: 22412385 The Transcription Factor C/EBP Delta Has Anti-apoptotic and Anti-inflammatory Roles in Pancreatic Beta Cells PloS One. 2012 | Pubmed ID: 22347430 Long-term (5 Years) Efficacy and Safety of Pancreas Transplantation Alone in Type 1 Diabetic Patients Transplantation. Apr, 2012 | Pubmed ID: 22314339 DNA Methylation Profiling Identifies Epigenetic Dysregulation in Pancreatic Islets from Type 2 Diabetic Patients The EMBO Journal. Mar, 2012 | Pubmed ID: 22293752 Laparoscopic Robot-assisted Pancreas Transplantation: First World Experience Transplantation. Jan, 2012 | Pubmed ID: 22245834 Nanomedicine for Treatment of Diabetes in an Aging Population: State-of-the-art and Future Developments Maturitas. Sep, 2012 | Pubmed ID: 22209199 Results of Pancreas Transplantation Alone with Special Attention to Native Kidney Function and Proteinuria in Type 1 Diabetes Patients The Review of Diabetic Studies : RDS. 2011 | Pubmed ID: 22189549 Altered Insulin Receptor Signalling and β-cell Cycle Dynamics in Type 2 Diabetes Mellitus PloS One. 2011 | Pubmed ID: 22140505 PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic β-cell Apoptosis Via Regulation of the BH3-only Protein Bim Diabetes. Dec, 2011 | Pubmed ID: 21984578 Cytokines Tumor Necrosis Factor-α and Interferon-γ Induce Pancreatic β-cell Apoptosis Through STAT1-mediated Bim Protein Activation The Journal of Biological Chemistry. Nov, 2011 | Pubmed ID: 21937453 Pleiotropic Effects of GIP on Islet Function Involve Osteopontin Diabetes. Sep, 2011 | Pubmed ID: 21810601 Zinc Transporter 8 Autoantibodies Increase the Predictive Value of Islet Autoantibodies for Function Loss of Technically Successful Solitary Pancreas Transplant Transplantation. Sep, 2011 | Pubmed ID: 21792090 Histopathology and Ex Vivo Insulin Secretion of Pancreatic Islets in Gestational Diabetes: A Case Report Islets. Sep-Oct, 2011 | Pubmed ID: 21765242 Current Perspectives on Laparoscopic Robot-assisted Pancreas and Pancreas-kidney Transplantation The Review of Diabetic Studies : RDS. 2011 | Pubmed ID: 21720670 Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-mediated β-cell Death Diabetes. Aug, 2011 | Pubmed ID: 21659501 ENPP1 Affects Insulin Action and Secretion: Evidences from in Vitro Studies PloS One. 2011 | Pubmed ID: 21573217 The Liver Receptor Homolog-1 (LRH-1) is Expressed in Human Islets and Protects {beta}-cells Against Stress-induced Apoptosis Human Molecular Genetics. Jul, 2011 | Pubmed ID: 21536586 Neutralizing Interleukin-1beta (IL-1beta) Induces Beta-cell Survival by Maintaining PDX1 Protein Nuclear Localization The Journal of Biological Chemistry. May, 2011 | Pubmed ID: 21393239 Segmental Live Donor Pancreas Transplantation: Review and Critique of Rationale, Outcomes, and Current Recommendations Clinical Transplantation. Jan-Feb, 2011 | Pubmed ID: 21158928 Class II Phosphoinositide 3-kinase Regulates Exocytosis of Insulin Granules in Pancreatic Beta Cells The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21127054 Pancreas Rejection After Pandemic Influenzavirus A(H1N1) Vaccination or Infection: a Report of Two Cases Transplant International : Official Journal of the European Society for Organ Transplantation. Mar, 2011 | Pubmed ID: 21121966 The Emerging Role of Autophagy in the Pathophysiology of Diabetes Mellitus Autophagy. Jan, 2011 | Pubmed ID: 20935516 EuroDia: a Beta-cell Gene Expression Resource Database : the Journal of Biological Databases and Curation. 2010 | Pubmed ID: 20940178 Gene Expression Profiles of Beta-cell Enriched Tissue Obtained by Laser Capture Microdissection from Subjects with Type 2 Diabetes PloS One. 2010 | Pubmed ID: 20644627 Genetic and Functional Assessment of the Role of the Rs13431652-A and Rs573225-A Alleles in the G6PC2 Promoter That Are Strongly Associated with Elevated Fasting Glucose Levels Diabetes. Oct, 2010 | Pubmed ID: 20622168 Type 2 Diabetes Susceptibility Gene Expression in Normal or Diabetic Sorted Human Alpha and Beta Cells: Correlations with Age or BMI of Islet Donors PloS One. 2010 | Pubmed ID: 20548773 P53 Up-regulated Modulator of Apoptosis (PUMA) Activation Contributes to Pancreatic Beta-cell Apoptosis Induced by Proinflammatory Cytokines and Endoplasmic Reticulum Stress The Journal of Biological Chemistry. Jun, 2010 | Pubmed ID: 20421300 Exendin-4 Prevents C-Jun N-terminal Protein Kinase Activation by Tumor Necrosis Factor-alpha (TNFalpha) and Inhibits TNFalpha-induced Apoptosis in Insulin-secreting Cells Endocrinology. May, 2010 | Pubmed ID: 20219981 Improved Protocol For Laser Microdissection Of Human Pancreatic Islets From Surgical Specimens Dorothée Sturm1,2, Lorella Marselli3, Florian Ehehalt1,2, Daniela Richter1, Marius Distler2, Stephan Kersting1,2, Robert Grützmann2, Krister Bokvist4, Philippe Froguel5, Robin Liechti6, Anne Jörns7, Paolo Meda8, Gustavo Bruno Baretton9, Hans-Detlev Saeger2, Anke M. Schulte10, Piero Marchetti3, Michele Solimena1 1Molecular Diabetology, Paul Langerhans Institute Dresden, 2Department of GI-, Thoracic- and Vascular Surgery, University Hospital Carl Gustav Carus, University of Technology Dresden, 3Department of Endocrinology and Metabolism, Metabolic Unit University of Pisa, 4Labs DC0522, Lilly Corporate Center, 5Genomics, Faculty of Medicine Imperial College London, 6Vital-IT, SIB Swiss Institute of Bioinformatics, 7Clinical Biochemistry, Hannover Medical School, 8Cell Physiology and Metabolism, Medical School, University of Geneva, 9Department of Pathology, University Hospital Carl Gustav Carus, University of Technology Dresden, 10R&D DIAB Division / Translational Medicine, Sanofi-Aventis JoVE 50231 Medicine
Improved Protocol For Laser Microdissection Of Human Pancreatic Islets From Surgical Specimens Dorothée Sturm1,2, Lorella Marselli3, Florian Ehehalt1,2, Daniela Richter1, Marius Distler2, Stephan Kersting1,2, Robert Grützmann2, Krister Bokvist4, Philippe Froguel5, Robin Liechti6, Anne Jörns7, Paolo Meda8, Gustavo Bruno Baretton9, Hans-Detlev Saeger2, Anke M. Schulte10, Piero Marchetti3, Michele Solimena1 1Molecular Diabetology, Paul Langerhans Institute Dresden, 2Department of GI-, Thoracic- and Vascular Surgery, University Hospital Carl Gustav Carus, University of Technology Dresden, 3Department of Endocrinology and Metabolism, Metabolic Unit University of Pisa, 4Labs DC0522, Lilly Corporate Center, 5Genomics, Faculty of Medicine Imperial College London, 6Vital-IT, SIB Swiss Institute of Bioinformatics, 7Clinical Biochemistry, Hannover Medical School, 8Cell Physiology and Metabolism, Medical School, University of Geneva, 9Department of Pathology, University Hospital Carl Gustav Carus, University of Technology Dresden, 10R&D DIAB Division / Translational Medicine, Sanofi-Aventis JoVE 50231 Medicine