Robert Sikes Biological Sciences University of Delaware Biography Publications Institution JoVE Articles Robert Sikes has not added a biography. If you are Robert Sikes and would like to personalize this page please email our Author Liaison for assistance. Publications Increased TGF-β1-mediated Suppression of Growth and Motility in Castrate-resistant Prostate Cancer Cells is Consistent with Smad2/3 Signaling The Prostate. Jan, 2012 | Pubmed ID: 22228025 Overexpression of the VSSC-associated CAM, Beta-2, Enhances LNCaP Cell Metastasis Associated Behavior The Prostate. Nov, 2011 | Pubmed ID: 22127840 Effect of Moderate-to-severe Chronic Kidney Disease on Flow-mediated Dilation and Progenitor Cells Experimental Biology and Medicine (Maywood, N.J.). Sep, 2011 | Pubmed ID: 21791552 Organization of Somatosensory Cortex in the Northern Grasshopper Mouse (Onychomys Leucogaster), a Predatory Rodent The Journal of Comparative Neurology. Jan, 2011 | Pubmed ID: 21120928 Energy Digestibility of Giant Pandas on Bamboo-only and on Supplemented Diets Zoo Biology. Mar-Apr, 2011 | Pubmed ID: 20814990 Paracrine Factors Produced by Bone Marrow Stromal Cells Induce Apoptosis and Neuroendocrine Differentiation in Prostate Cancer Cells The Prostate. Feb, 2011 | Pubmed ID: 20665531 Osteoblasts Can Stimulate Prostate Cancer Growth and Transcriptionally Down-regulate PSA Expression in Cell Line Models Urologic Oncology. Nov, 2011 | Pubmed ID: 20451417 Androgen Mediated Translational and Postranslational Regulation of IGFBP-2 in Androgen-sensitive LNCaP Human Prostate Cancer Cells American Journal of Translational Research. 2010 | Pubmed ID: 20407609 Nociceptive Processing by Anterior Cingulate Pyramidal Neurons Journal of Neurophysiology. Jun, 2010 | Pubmed ID: 20357067 Short-term Intermittent PTH 1-34 Administration Enhances Bone Formation in SCID/Beige Mice Endocrine Journal. 2010 | Pubmed ID: 20139633 The Developmental Expression Profile of PAX2 in the Murine Prostate The Prostate. May, 2010 | Pubmed ID: 20017165 Human Prostate Fibroblasts Induce Growth and Confer Castration Resistance and Metastatic Potential in LNCaP Cells European Urology. Jul, 2010 | Pubmed ID: 19747763 Disease Evidence for IGFBP-2 As a Key Player in Prostate Cancer Progression and Development of Osteosclerotic Lesions American Journal of Translational Research. 2009 | Pubmed ID: 19956425 Osteosclerotic Prostate Cancer Metastasis to Murine Bone Are Enhanced with Increased Bone Formation Clinical & Experimental Metastasis. 2009 | Pubmed ID: 19421879 Quantitative Modeling and Analysis of the Transforming Growth Factor Beta Signaling Pathway Biophysical Journal. Mar, 2009 | Pubmed ID: 19254534 Conserved Gene Expression Programs Integrate Mammalian Prostate Development and Tumorigenesis Cancer Research. Mar, 2009 | Pubmed ID: 19223557 Novel Surface Expression of Reticulocalbin 1 on Bone Endothelial Cells and Human Prostate Cancer Cells is Regulated by TNF-alpha Journal of Cellular Biochemistry. Aug, 2008 | Pubmed ID: 18561328 Norepinephrinergic Afferents and Cytology of the Macaque Monkey Midline, Mediodorsal, and Intralaminar Thalamic Nuclei Brain Structure & Function. Aug, 2008 | Pubmed ID: 18317800 Distribution and Properties of Visceral Nociceptive Neurons in Rabbit Cingulate Cortex Pain. Mar, 2008 | Pubmed ID: 18022321 Variation in Digestive Efficiency of Captive North American River Otters (Lontra Canadensis) on Various Diets Zoo Biology. Jan, 2007 | Pubmed ID: 19360560 Hormonal Regulation of IGFBP-2 Proteolysis is Attenuated with Progression to Androgen Insensitivity in the LNCaP Progression Model Journal of Cellular Physiology. Oct, 2007 | Pubmed ID: 17492783 Androgen-independent Growth and Tumorigenesis of Prostate Cancer Cells Are Enhanced by the Presence of PKA-differentiated Neuroendocrine Cells Cancer Research. Apr, 2007 | Pubmed ID: 17440078 Voltage-sensitive Ion Channels and Cancer Cancer Metastasis Reviews. Sep, 2006 | Pubmed ID: 17111226 Met-Independent Hepatocyte Growth Factor-mediated Regulation of Cell Adhesion in Human Prostate Cancer Cells BMC Cancer. 2006 | Pubmed ID: 16869958 Gene Expression in the LNCaP Human Prostate Cancer Progression Model: Progression Associated Expression in Vitro Corresponds to Expression Changes Associated with Prostate Cancer Progression in Vivo Cancer Letters. Dec, 2006 | Pubmed ID: 16500022 Increased Insulin-like Growth Factor I Receptor Expression and Signaling Are Components of Androgen-independent Progression in a Lineage-derived Prostate Cancer Progression Model Cancer Research. Dec, 2004 | Pubmed ID: 15574769 Thalidomide and Analogues: Current Proposed Mechanisms and Therapeutic Usage Clinical Prostate Cancer. Jun, 2004 | Pubmed ID: 15279692 Cellular Interactions in the Tropism of Prostate Cancer to Bone International Journal of Cancer. Journal International Du Cancer. Jul, 2004 | Pubmed ID: 15122581 Cancer Cells Homing to Bone: the Significance of Chemotaxis and Cell Adhesion Cancer Treatment and Research. 2004 | Pubmed ID: 15043197 Changes in Extracellular Matrix (ECM) and ECM-associated Proteins in the Metastatic Progression of Prostate Cancer Reproductive Biology and Endocrinology : RB&E. Jan, 2004 | Pubmed ID: 14711377 Therapeutic Approaches Targeting Prostate Cancer Progression Using Novel Voltage-gated Ion Channel Blockers Clinical Prostate Cancer. Dec, 2003 | Pubmed ID: 15040863 Expressed Sequence Tag Profiling Identifies Developmental and Anatomic Partitioning of Gene Expression in the Mouse Prostate Genome Biology. 2003 | Pubmed ID: 14659016 Voltage-gated Sodium Channel Blockers As Cytostatic Inhibitors of the Androgen-independent Prostate Cancer Cell Line PC-3 Molecular Cancer Therapeutics. Nov, 2003 | Pubmed ID: 14617788 Insulin-like Growth Factor Binding Protein-related Protein 1 (IGFBP-rP1/mac 25) is Reduced in Human Prostate Cancer and is Inversely Related to Tumor Volume and Proliferation Index in Lucap 23.12 Xenografts The Prostate. Jul, 2003 | Pubmed ID: 12746836 Constitutive Activation of the Ras/mitogen-activated Protein Kinase Signaling Pathway Promotes Androgen Hypersensitivity in LNCaP Prostate Cancer Cells Cancer Research. Apr, 2003 | Pubmed ID: 12702592 The Role of Insulin-like Growth Factor-II in Cancer Growth and Progression Evidenced by the Use of Ribozymes and Prostate Cancer Progression Models Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Feb, 2003 | Pubmed ID: 12550081 Peptides from Phage Display Library Modulate Gene Expression in Mesenchymal Cells and Potentiate Osteogenesis in Unicortical Bone Defects Gary Balian1, Gina Beck1, Vedavathi Madhu1, Robert Sikes2, Quanjun Cui3, Haixiang Liang1, Joshua Bush1 1Orthopaedics Research, University of Virginia, 2Biological Sciences, University of Delaware, 3Orthopaedic Surgery, University of Virginia JoVE 2362 Biology
Peptides from Phage Display Library Modulate Gene Expression in Mesenchymal Cells and Potentiate Osteogenesis in Unicortical Bone Defects Gary Balian1, Gina Beck1, Vedavathi Madhu1, Robert Sikes2, Quanjun Cui3, Haixiang Liang1, Joshua Bush1 1Orthopaedics Research, University of Virginia, 2Biological Sciences, University of Delaware, 3Orthopaedic Surgery, University of Virginia JoVE 2362 Biology