Vittorio Sartorelli Laboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis, Musculoskeletal, and Skin Diseases (NIAMS) National Institutes of Health (NIH) Biography Publications Institution JoVE Articles Vittorio Sartorelli has not added a biography. If you are Vittorio Sartorelli and would like to personalize this page please email our Author Liaison for assistance. Publications Single Cell Analysis of Adult Mouse Skeletal Muscle Stem Cells in Homeostatic and Regenerative Conditions Development (Cambridge, England). 04, 2019 | Pubmed ID: 30890574 ATP Citrate Lyase: A New Player Linking Skeletal Muscle Metabolism and Epigenetics Trends in Endocrinology and Metabolism: TEM. Apr, 2018 | Pubmed ID: 29395431 The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins Molecular Cell. Oct, 2017 | Pubmed ID: 29033324 Specific Sirt1 Activator-mediated Improvement in Glucose Homeostasis Requires Sirt1-Independent Activation of AMPK EBioMedicine. Apr, 2017 | Pubmed ID: 28396013 Roles of H3K27me2 and H3K27me3 Examined During Fate Specification of Embryonic Stem Cells Cell Reports. Oct, 2016 | Pubmed ID: 27783950 S6K1ing to ResTOR Adipogenesis with Polycomb Molecular Cell. 05, 2016 | Pubmed ID: 27153531 Laminopathies Disrupt Epigenomic Developmental Programs and Cell Fate Science Translational Medicine. 04, 2016 | Pubmed ID: 27099177 Polycomb Ezh2 Controls the Fate of GABAergic Neurons in the Embryonic Cerebellum Development (Cambridge, England). 06, 2016 | Pubmed ID: 27068104 The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1 Cell Reports. Feb, 2016 | Pubmed ID: 26832413 Metabolic Reprogramming of Stem Cell Epigenetics Cell Stem Cell. Dec, 2015 | Pubmed ID: 26637942 IL-6 Blockade As a Therapeutic Approach for Duchenne Muscular Dystrophy EBioMedicine. Apr, 2015 | Pubmed ID: 26137566 EZH2 is Crucial for Both Differentiation of Regulatory T Cells and T Effector Cell Expansion Scientific Reports. Jun, 2015 | Pubmed ID: 26090605 Super-enhancers Delineate Disease-associated Regulatory Nodes in T Cells Nature. Apr, 2015 | Pubmed ID: 25686607 The NAD(+)-dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells Cell Stem Cell. Feb, 2015 | Pubmed ID: 25600643 Gcn5 and PCAF Regulate PPARγ and Prdm16 Expression to Facilitate Brown Adipogenesis Molecular and Cellular Biology. Oct, 2014 | Pubmed ID: 25071153 An Evolutionarily Biased Distribution of MiRNA Sites Toward Regulatory Genes with High Promoter-driven Intrinsic Transcriptional Noise BMC Evolutionary Biology. Apr, 2014 | Pubmed ID: 24707827 The Emerging Roles of ERNAs in Transcriptional Regulatory Networks RNA Biology. 2014 | Pubmed ID: 24525859 H3K4 Mono- and Di-methyltransferase MLL4 is Required for Enhancer Activation During Cell Differentiation ELife. Dec, 2013 | Pubmed ID: 24368734 Interactome Maps of Mouse Gene Regulatory Domains Reveal Basic Principles of Transcriptional Regulation Cell. Dec, 2013 | Pubmed ID: 24360274 ERNAs Promote Transcription by Establishing Chromatin Accessibility at Defined Genomic Loci Molecular Cell. Sep, 2013 | Pubmed ID: 23993744 The Methyltransferase SMYD3 Mediates the Recruitment of Transcriptional Cofactors at the Myostatin and C-Met Genes and Regulates Skeletal Muscle Atrophy Genes & Development. Jun, 2013 | Pubmed ID: 23752591 BACH2 Represses Effector Programs to Stabilize T(reg)-mediated Immune Homeostasis Nature. Jun, 2013 | Pubmed ID: 23728300 The Histone Chaperone Spt6 Coordinates Histone H3K27 Demethylation and Myogenesis The EMBO Journal. Apr, 2013 | Pubmed ID: 23503590 STATs Shape the Active Enhancer Landscape of T Cell Populations Cell. Nov, 2012 | Pubmed ID: 23178119 Polycomb Protein Ezh1 Promotes RNA Polymerase II Elongation Molecular Cell. Jan, 2012 | Pubmed ID: 22196887 Who Needs Microtubules? Myogenic Reorganization of MTOC, Golgi Complex and ER Exit Sites Persists Despite Lack of Normal Microtubule Tracks PloS One. 2011 | Pubmed ID: 22216166 Decreased MicroRNA-214 Levels in Breast Cancer Cells Coincides with Increased Cell Proliferation, Invasion and Accumulation of the Polycomb Ezh2 Methyltransferase Carcinogenesis. Nov, 2011 | Pubmed ID: 21828058 Sculpting Chromatin Beyond the Double Helix: Epigenetic Control of Skeletal Myogenesis Current Topics in Developmental Biology. 2011 | Pubmed ID: 21621067 Polycomb EZH2 Controls Self-renewal and Safeguards the Transcriptional Identity of Skeletal Muscle Stem Cells Genes & Development. Apr, 2011 | Pubmed ID: 21498568 Phosphoryl-EZH-ion Cell Stem Cell. Mar, 2011 | Pubmed ID: 21362566 Myc-nick: the Force Behind C-Myc Science Signaling. Dec, 2010 | Pubmed ID: 21156935 TNF/p38α/polycomb Signaling to Pax7 Locus in Satellite Cells Links Inflammation to the Epigenetic Control of Muscle Regeneration Cell Stem Cell. Oct, 2010 | Pubmed ID: 20887952 Dietary Restriction: Standing Up for Sirtuins Science (New York, N.Y.). Aug, 2010 | Pubmed ID: 20798296 MicroRNA-214 and Polycomb Group Proteins: a Regulatory Circuit Controlling Differentiation and Cell Fate Decisions Cell Cycle (Georgetown, Tex.). Apr, 2010 | Pubmed ID: 20372071 Mir-214-dependent Regulation of the Polycomb Protein Ezh2 in Skeletal Muscle and Embryonic Stem Cells Molecular Cell. Oct, 2009 | Pubmed ID: 19818710 Comparing and Contrasting the Roles of AMPK and SIRT1 in Metabolic Tissues Cell Cycle (Georgetown, Tex.). Dec, 2008 | Pubmed ID: 19029811 Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 Through AMPK-mediated Regulation of Nampt Developmental Cell. May, 2008 | Pubmed ID: 18477450 MyoD Acetylation Influences Temporal Patterns of Skeletal Muscle Gene Expression The Journal of Biological Chemistry. Dec, 2007 | Pubmed ID: 17965412 The DEAD-box P68/p72 Proteins and the Noncoding RNA Steroid Receptor Activator SRA: Eclectic Regulators of Disparate Biological Functions Cell Cycle (Georgetown, Tex.). May, 2007 | Pubmed ID: 17495528 The RNA Helicases P68/p72 and the Noncoding RNA SRA Are Coregulators of MyoD and Skeletal Muscle Differentiation Developmental Cell. Oct, 2006 | Pubmed ID: 17011493 Follistatin Induction by Nitric Oxide Through Cyclic GMP: a Tightly Regulated Signaling Pathway That Controls Myoblast Fusion The Journal of Cell Biology. Jan, 2006 | Pubmed ID: 16401724 Fgfr4 is Required for Effective Muscle Regeneration in Vivo. Delineation of a MyoD-Tead2-Fgfr4 Transcriptional Pathway The Journal of Biological Chemistry. Jan, 2006 | Pubmed ID: 16267055 Mechanisms Underlying the Transcriptional Regulation of Skeletal Myogenesis Current Opinion in Genetics & Development. Oct, 2005 | Pubmed ID: 16055324 The Polycomb Ezh2 Methyltransferase Regulates Muscle Gene Expression and Skeletal Muscle Differentiation Genes & Development. Nov, 2004 | Pubmed ID: 15520282 Molecular and Cellular Determinants of Skeletal Muscle Atrophy and Hypertrophy Science's STKE : Signal Transduction Knowledge Environment. Jul, 2004 | Pubmed ID: 15292521 Tax Relieves Transcriptional Repression by Promoting Histone Deacetylase 1 Release from the Human T-cell Leukemia Virus Type 1 Long Terminal Repeat Journal of Virology. Jul, 2004 | Pubmed ID: 15194748 Deacetylase Inhibitors Increase Muscle Cell Size by Promoting Myoblast Recruitment and Fusion Through Induction of Follistatin Developmental Cell. May, 2004 | Pubmed ID: 15130492 Sir2 Regulates Skeletal Muscle Differentiation As a Potential Sensor of the Redox State Molecular Cell. Jul, 2003 | Pubmed ID: 12887892 Stage-specific Modulation of Skeletal Myogenesis by Inhibitors of Nuclear Deacetylases Proceedings of the National Academy of Sciences of the United States of America. May, 2002 | Pubmed ID: 12032356 The Link Between Chromatin Structure, Protein Acetylation and Cellular Differentiation Frontiers in Bioscience : a Journal and Virtual Library. Sep, 2001 | Pubmed ID: 11532612 HERP, a Novel Heterodimer Partner of HES/E(spl) in Notch Signaling Molecular and Cellular Biology. Sep, 2001 | Pubmed ID: 11486045 HERP, a New Primary Target of Notch Regulated by Ligand Binding Molecular and Cellular Biology. Sep, 2001 | Pubmed ID: 11486044 Proteasome-mediated Degradation of the Coactivator P300 Impairs Cardiac Transcription Molecular and Cellular Biology. Dec, 2000 | Pubmed ID: 11073966 FACS-Isolation and Culture of Fibro-Adipogenic Progenitors and Muscle Stem Cells from Unperturbed and Injured Mouse Skeletal Muscle Giulia Riparini1, James M. Simone2, Vittorio Sartorelli1 1Laboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis, Musculoskeletal, and Skin Diseases (NIAMS), National Institutes of Health (NIH), 2Flow Cytometry Section, National Institute of Arthritis, Musculoskeletal, and Skin Diseases (NIAMS), National Institutes of Health (NIH) JoVE 63983 Developmental Biology Identification of Skeletal Muscle Satellite Cells by Immunofluorescence with Pax7 and Laminin Antibodies Xuesong Feng*1, Faiza Naz*2, Aster H. Juan1, Stefania Dell'Orso2, Vittorio Sartorelli1 1Laboratory of Muscle Stem Cells and Gene Regulation, National Institutes of Health, 2Office of Science and Technology, National Institute of Arthritis, Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health JoVE 57212 Developmental Biology
FACS-Isolation and Culture of Fibro-Adipogenic Progenitors and Muscle Stem Cells from Unperturbed and Injured Mouse Skeletal Muscle Giulia Riparini1, James M. Simone2, Vittorio Sartorelli1 1Laboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis, Musculoskeletal, and Skin Diseases (NIAMS), National Institutes of Health (NIH), 2Flow Cytometry Section, National Institute of Arthritis, Musculoskeletal, and Skin Diseases (NIAMS), National Institutes of Health (NIH) JoVE 63983 Developmental Biology
Identification of Skeletal Muscle Satellite Cells by Immunofluorescence with Pax7 and Laminin Antibodies Xuesong Feng*1, Faiza Naz*2, Aster H. Juan1, Stefania Dell'Orso2, Vittorio Sartorelli1 1Laboratory of Muscle Stem Cells and Gene Regulation, National Institutes of Health, 2Office of Science and Technology, National Institute of Arthritis, Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health JoVE 57212 Developmental Biology
