Xiaoan Ruan Genome Institute of Singapore Agency for Science, Technology and Research, Singapore Biography Publications Institution JoVE Articles Xiaoan Ruan has not added a biography. If you are Xiaoan Ruan and would like to personalize this page please email our Author Liaison for assistance. Publications A Common BIM Deletion Polymorphism Mediates Intrinsic Resistance and Inferior Responses to Tyrosine Kinase Inhibitors in Cancer Nature Medicine. 2012 | Pubmed ID: 22426421 Extensive Promoter-centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation Cell. Jan, 2012 | Pubmed ID: 22265404 Genome Wide Full-length Transcript Analysis Using 5' and 3' Paired-end-tag Next Generation Sequencing (RNA-PET) Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22113299 Comprehensive Long-span Paired-end-tag Mapping Reveals Characteristic Patterns of Structural Variations in Epithelial Cancer Genomes Genome Research. May, 2011 | Pubmed ID: 21467267 Transcriptional Consequences of Genomic Structural Aberrations in Breast Cancer Genome Research. May, 2011 | Pubmed ID: 21467264 Genome-wide Analysis Reveals Methyl-CpG-binding Protein 2-dependent Regulation of MicroRNAs in a Mouse Model of Rett Syndrome Proceedings of the National Academy of Sciences of the United States of America. Oct, 2010 | Pubmed ID: 20921386 Chromatin Interaction Analysis Using Paired-end Tag Sequencing Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [et Al.]. Jan, 2010 | Pubmed ID: 20069536 An Oestrogen-receptor-alpha-bound Human Chromatin Interactome Nature. Nov, 2009 | Pubmed ID: 19890323 Elevated Phosphorus Modulates Vitamin D Receptor-mediated Gene Expression in Human Vascular Smooth Muscle Cells American Journal of Physiology. Renal Physiology. Nov, 2007 | Pubmed ID: 17715259 Mechanistic Analysis of VDR-mediated Renin Suppression Nephron. Physiology. 2007 | Pubmed ID: 17687191 VDR-mediated Gene Expression Patterns in Resting Human Coronary Artery Smooth Muscle Cells Journal of Cellular Biochemistry. Apr, 2007 | Pubmed ID: 17115413 Expression of VDR and CYP24A1 MRNA in Human Tumors Cancer Chemotherapy and Pharmacology. Jan, 2006 | Pubmed ID: 16180015 Effects of Vitamin D Analogs on Gene Expression Profiling in Human Coronary Artery Smooth Muscle Cells Atherosclerosis. May, 2006 | Pubmed ID: 16095599 SiRNA-mediated Off-target Gene Silencing Triggered by a 7 Nt Complementation Nucleic Acids Research. 2005 | Pubmed ID: 16091630 Novel Approach to Mapping of Resistance Mutations in Whole Genomes by Using Restriction Enzyme Modulation of Transformation Efficiency Antimicrobial Agents and Chemotherapy. Jul, 2005 | Pubmed ID: 15980348 Cardiovascular Disease in Chronic Kidney Failure: is There a Role for Vitamin D Analogs? Current Opinion in Investigational Drugs (London, England : 2000). Mar, 2005 | Pubmed ID: 15816500 Ribosome Affinity and the Prolonged Molecular Postantibiotic Effect of Cethromycin (ABT-773) in Haemophilus Influenzae International Journal of Antimicrobial Agents. Oct, 2004 | Pubmed ID: 15380262 Novel Antibacterial Class Antimicrobial Agents and Chemotherapy. Dec, 2003 | Pubmed ID: 14638491 A Strategy for High-throughput Assay Development Using Leads Derived from Nuclear Magnetic Resonance-based Screening Journal of Biomolecular Screening. Oct, 2002 | Pubmed ID: 14599358 Chromatin Interaction Analysis with Paired-End Tag Sequencing (ChIA-PET) for Mapping Chromatin Interactions and Understanding Transcription Regulation Yufen Goh*1, Melissa J. Fullwood*1,2,3, Huay Mei Poh1, Su Qin Peh1, Chin Thing Ong1, Jingyao Zhang1, Xiaoan Ruan1, Yijun Ruan1,3 1Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, 2A*STAR-Duke-NUS Neuroscience Research Partnership, Singapore, 3Department of Biochemistry, National University of Singapore, Singapore JoVE 3770 Biology
Chromatin Interaction Analysis with Paired-End Tag Sequencing (ChIA-PET) for Mapping Chromatin Interactions and Understanding Transcription Regulation Yufen Goh*1, Melissa J. Fullwood*1,2,3, Huay Mei Poh1, Su Qin Peh1, Chin Thing Ong1, Jingyao Zhang1, Xiaoan Ruan1, Yijun Ruan1,3 1Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, 2A*STAR-Duke-NUS Neuroscience Research Partnership, Singapore, 3Department of Biochemistry, National University of Singapore, Singapore JoVE 3770 Biology