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二维和三维活细胞成像的DNA损伤反应蛋白

JoVE 杂志
生物学

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JoVE 杂志生物学

Two- and Three-Dimensional Live Cell Imaging of DNA Damage Response Proteins

二维和三维活细胞成像的DNA损伤反应蛋白

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14,044 Views

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10:24 min

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September 28, 2012

DOI:

DOI:

•

10:24 min

September 28, 2012

•

2 Views

Jason M. Beckta^1,2, Scott C. Henderson³, Kristoffer Valerie^1,2,4

¹Department of Radiation Oncology,Virginia Commonwealth University, ²Department of Biochemistry & Molecular Biology,Virginia Commonwealth University, ³Department of Anatomy & Neurobiology,Virginia Commonwealth University, ⁴Massey Cancer Center,Virginia Commonwealth University

Summary

该协议描述了一个可视化的DNA双链断裂以及其定位在有丝分裂过程中DNA损伤激活的信号蛋白的方法。

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