高含量<em>体外</em>胰岛β细胞复制发现平台
11,115 Views
•
09:35 min
•
July 16, 2016
DOI:
成績單
Automatically generated
Summary
Automatically generated
对于糖尿病研究领域的关键挑战是要明白，调节胰岛β细胞的复制，并制定刺激β细胞再生方法的分子机制。在此高内涵筛选的方法来识别和评估小分子的β细胞复制促进活性表示。
Related Videos
09:31
In Vitro Colony Assays for Characterizing Tri-potent Progenitor Cells Isolated from the Adult Murine Pancreas
Related Videos
9414 Views
09:31
Assessing Replication and Beta Cell Function in Adenovirally-transduced Isolated Rodent Islets
Related Videos
13952 Views
05:51
Coculture Analysis of Extracellular Protein Interactions Affecting Insulin Secretion by Pancreatic Beta Cells
Related Videos
12864 Views
10:05
Single-cell Transcriptomic Analyses of Mouse Pancreatic Endocrine Cells
Related Videos
10904 Views
09:31
Sustained Administration of β-cell Mitogens to Intact Mouse Islets Ex Vivo Using Biodegradable Poly(lactic-co-glycolic acid) Microspheres
Related Videos
7198 Views
10:12
Differentiation of Human Pluripotent Stem Cells Into Pancreatic Beta-Cell Precursors in a 2D Culture System
Related Videos
2664 Views
08:41
Differentiation of Human Pluripotent Stem Cells into Insulin-Producing Islet Clusters
Related Videos
2725 Views
12:33
A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination
Related Videos
65121 Views
09:09
Pancreatic Islet Embedding for Paraffin Sections
Related Videos
12687 Views
08:04
Human Pseudoislet System for Synchronous Assessment of Fluorescent Biosensor Dynamics and Hormone Secretory Profiles
Related Videos
1846 Views
Read Article
Cite this Article
Zhao, Z., Abdolazimi, Y., Armstrong, N. A., Annes, J. P. A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform. J. Vis. Exp. (113), e54298, doi:10.3791/54298 (2016).
Copy