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Methoden Alternative Promoter Verwendung und Transkriptions-Verordnung von Murine Bcrp1 zu entdecken
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Methoden Alternative Promoter Verwendung und Transkriptions-Verordnung von Murine Bcrp1 zu entdecken

Article DOI: 10.3791/53827-v • 11:02 min • May 27th, 2016
May 27th, 2016 •
1,2, 1,3, 4, 5,6, 7, 1,3,8,9, 1,3,8,9,10,11
1Greenebaum Cancer Center, University of Maryland School of Medicine, 2Pharmaceutical Sciences, University of Maryland School of Pharmacy, 3Baltimore VA Medical Center, 4Membrane Transport and Biopharmaceutics, School of Pharmaceutical Sciences, Kanazawa University, 5Obstetrics, Gynecology and Reproductive Science, University of Pittsburgh, 6Magee Women's Research Institute, 7Obstetrics, Gynecology, Perinatal Research Branch (NICHD), Wayne State University School of Medicine, 8Medicine, University of Maryland School of Medicine, 9Pathology, University of Maryland School of Medicine, 10Pharmacology, University of Maryland School of Medicine, 11Experimental Therapeutics, University of Maryland School of Medicine

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Mit dem murinen ABC transporter Bcrp1 (ABCG2) als Beispiel in-silico - Protokolle werden dargestellt , um alternative Promotor Gebrauch in Gene in Mausgeweben exprimiert erkennen und die Funktionalität der alternativen Promotoren unter Verwendung von Reporter - Assays identifiziert , zu bewerten.

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Medizin Heft 111 Promoter Bcrp1 alternative Promotor-Nutzung E1U Mäusehoden steroidogenen Faktor-1
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