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JoVE Journal Bioengineering
Evaluering af hjertekontraktilitetsmodulationsterapi i 2D humane stamcelleafledte kardiomyocytter
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Evaluering af hjertekontraktilitetsmodulationsterapi i 2D humane stamcelleafledte kardiomyocytter

Article DOI: 10.3791/64848-v • 08:47 min • December 16th, 2022
December 16th, 2022 •
1, 1, 1, 1
1Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U.S. Food and Drug Administration

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Her demonstrerer vi en ikke-invasiv kontraktilitetsevalueringsmetode for hjertemedicinsk udstyr ved hjælp af 2D humant induceret pluripotent stamcelleafledt kardiomyocyt (hiPSC-CM) monolag, belagt på et fleksibelt substrat kombineret med videobaseret mikroskopi. Dette værktøj vil være nyttigt til in vitro-evaluering af kontraktile egenskaber af hjerteelektrofysiologiske enheder.

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Bioengineering udgave 190 2D hiPSC-CM hjertekontraktilitetsmodulation kardiomyocytter kontraktilitet stamceller
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