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Cellular Structures: Components of a cell.

An Introduction to Cellular and Molecular Neuroscience

JoVE 5213

Cellular and molecular neuroscience is one of the newest and fastest growing subdisciplines in neuroscience. By investigating the influences of genes, signaling molecules, and cellular morphology, researchers in this field uncover crucial insights into normal brain development and function, as well as the root causes of many pathological conditions.


 Neuroscience

Density Gradient Ultracentrifugation

JoVE 5685

Density gradient ultracentrifugation is a common technique used to isolate and purify biomolecules and cell structures. This technique exploits the fact that, in suspension, particles that are more dense than the solvent will sediment, while those that are less dense will float. A high-speed ultracentrifuge is used to accelerate this process in order to separate biomolecules within a density…

 Biochemistry

Cell Structure- Concept

JoVE 10587

Background

Cells represent the most basic biological units of all organisms, whether it be simple, single-celled organisms like bacteria, or large, multicellular organisms like elephants and giant redwood trees. In the mid 19th century, the Cell Theory was proposed to define a cell, which states:



Every living organism is made up of one or more cells.
The cells…

 Lab Bio

An Introduction to Molecular Developmental Biology

JoVE 5328

Molecular signals play a major role in the complex processes occurring during embryonic development. These signals regulate activities such as cell differentiation and migration, which contribute to the formation of specific cell types and structures. The use of molecular approaches allows researchers to investigate these physical and chemical mechanisms in detail.


This video will …

 Developmental Biology

Chromosomal Theory of Inheritance

JoVE 11010

In 1866, Gregor Mendel published the results of his pea plant breeding experiments, providing evidence for predictable patterns in the inheritance of physical characteristics. The significance of his findings was not immediately recognized. In fact, the existence of genes was unknown at the time. Mendel referred to hereditary units as “factors.”

The mechanisms underlying Mendel’s observations—the basis of his laws of segregation and independent assortment—remained elusive. In the late 1800s, advances in microscopy and staining techniques allowed scientists to visualize mitosis and meiosis for the first time. In the early 1900s, Theodor Boveri, Walter Sutton, and others independently proposed that chromosomes may underlie Mendel’s laws—the chromosomal theory of inheritance. Researching sea urchins and grasshoppers, respectively, Boveri and Sutton noted striking similarities between chromosomes during meiosis and Mendel’s factors. Like Mendel’s factors, chromosomes come in pairs. Reminiscent of Mendel’s law of segregation, these pairs become separated during meiosis such that every gamete (e.g., sperm or egg) receives one chromosome from each pair. Chromosome pairs are segregated independently of one another, corresponding to Mendel’s law of independent assortment. The first conc

 Core: Classical and Modern Genetics

Cell Structure - Prep Student

JoVE 10631

Visualizing Onion and Cheek Cells
Immediately before the experiment, wash and peel onion bulbs for the class.
Remove the entire brown outer skin and cut the onion in half with a knife. Pull apart the layers of the onion. The thin, nearly transparent film layers within the onion will be used by the students.
Place the onion film into a Petri…

 Lab Bio

Imaging Dendritic Spines of Rat Primary Hippocampal Neurons using Structured Illumination Microscopy

1Center for Neuroscience, Swammerdam Institute for Life Sciences, University of Amsterdam, 2Van Leeuwenhoek Centre for Advanced Microscopy, Section Molecular Cytology, Swammerdam Institute for Life Sciences, University of Amsterdam

JoVE 51276

 Neuroscience

In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis

1Centre d'Etudes Nucléaires Bordeaux Gradignan (CENBG), Université de Bordeaux, 2Centre d'Etudes Nucléaires Bordeaux Gradignan (CENBG), CNRS, 3Institut de Chimie de la Matière Condens é e de Bordeaux (ICMCB), CNRS, 4Institut de Chimie de la Matière Condens é e de Bordeaux (ICMCB), Université de Bordeaux

JoVE 55041

 Chemistry

Time-lapse Imaging of Primary Preneoplastic Mammary Epithelial Cells Derived from Genetically Engineered Mouse Models of Breast Cancer

1Department of Oncology, Georgetown University, 2Lombardi Comprehensive Cancer Center, Georgetown University, 3Stem Cell Dynamics, Helmholtz Zentrum München - German Research Center for Environmental Health, 4Department of Medicine, Georgetown University, 5Department of Nanobiomedical Science and WCU Research Center of Nanobiomedical Science, Dankook University

JoVE 50198

 Medicine

Laser-Induced Fluorescence Emission (L.I.F.E.) as Novel Non-Invasive Tool for In-Situ Measurements of Biomarkers in Cryospheric Habitats

1Institute of Ecology, University of Innsbruck, 2Austrian Polar Research Institute, University of Vienna, 3BrainLinks-BrainTools, Bernstein Center Freiburg, 4Atom Science, Kasevich Lab, Stanford University, 5Institute of Experimental Physics, University of Innsbruck, 6Department of Physics, Extraterrestrial Vehicle Instruments Laboratory, Harvey Mudd College

Video Coming Soon

JoVE 60447

 JoVE In-Press

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery

1Department of Chemical Engineering, Northeastern University, 2Nanomedicine Science and Technology Center, Northeastern University, 3Department of Physics, Northeastern University, 4Departments of Bioengineering, Northeastern University, 5Department of Neuroscience, Albert Einstein College of Medicine

JoVE 56760

 Bioengineering
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