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 JoVE Behavior

Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome

1Institute of Statistical Science, Academia Sinica, 2Max Planck Institute for Human Cognitive and Brain Sciences, 3Department of Psychology, Fo Guang University, 4Department of Electrical Engineering, Fu Jen Catholic University, 5State Research Institute of Physiology and Basic Medicine, 6Novosibirsk State University, 7Imaging Research Center, Taipei Medical University


JoVE 53962

 JoVE Medicine

Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice

1Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute at Lake Nona, 2Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, 3Vanderbilt Mouse Metabolic Phenotyping Center, Vanderbilt University School of Medicine, 4Department of Pediatrics and Cellular and Integrative Physiology, Indiana University School of Medicine


JoVE 3188

 JoVE Behavior

Studying Food Reward and Motivation in Humans

1Department of Psychiatry, University of Cambridge, 2Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, 3Cambridgeshire & Peterborough NHS Foundation Trust, University of Cambridge, 4West Anglia Comprehensive Local Research Network, Addenbrooke's Hospital


JoVE 51281

 Science Education: Essentials of Sensation and Perception

Object Substitution Masking

JoVE Science Education

Source: Laboratory of Jonathan Flombaum—Johns Hopkins University

Visual masking is a term used by perceptual scientists to refer to a wide range of phenomena in which in an image is presented but not perceived by an observer because of the presentation of a second image. There are several different kinds of masking, many of them relatively intuitive and unsurprising. But one surprising and important type of masking is called Object Substitution Masking. It has been a focus of research in vision science since it was discovered, relatively recently, around 1997 by Enns and Di Lollo.1 This video will demonstrate standard procedures for how to conduct an object substitution experiment, how to analyze the results, and it will also explain the hypothesized causes for this unusual form of masking.

 Science Education: Essentials of Lab Animal Research

Compound Administration III

JoVE Science Education

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN

There are many commonly used routes for compound administration in laboratory mice and rats. However, certain protocols may require the use of less commonly used routes, including intradermal, intranasal, and intracranial injections. Specialized training is essential for these procedures to be performed successfully. Justification for these routes may need to be provided to gain Institutional Animal Care and Use Committee (IACUC) approval.

 Science Education: Essentials of Cognitive Psychology

Binocular Rivalry

JoVE Science Education

Source: Laboratory of Jonathan Flombaum—Johns Hopkins University

Why do people have two forward-facing eyes? By presenting the brain with two ever so slightly different images it becomes possible to comprehend visual problems that are far more difficult to process through a single eye. Chief among these is the problem of 3-D perception, seeing the world in three dimensions, despite retinal inputs in only two dimensions. What happens if each eye receives two completely different images? That does not happen in nature, to be sure, but it can be contrived in the laboratory in a set-up called binocular rivalry. Binocular rivalry is a common laboratory paradigm for investigating the ways that the brain integrates information from two eyes, and in recent years, the mechanisms responsible for producing conscious experience.

 JoVE Medicine

Development of an Algorithm to Perform a Comprehensive Study of Autonomic Dysreflexia in Animals with High Spinal Cord Injury Using a Telemetry Device

1International Collaboration on Repair Discoveries (ICORD), Faculty of Medicine, University of British Columbia, 2Department of Medicine, Division of Physical Medicine and Rehabilitation, University of British Columbia, GF Strong Rehabilitation Centre


JoVE 52809

 JoVE Medicine

Bronchoalveolar Lavage (BAL) for Research; Obtaining Adequate Sample Yield

1Biomedical Research Centre in Microbial Diseases, National Institute for Health Research, 2Respiratory Infection Group, Royal Liverpool and Broadgreen University Hospital Trust, 3Respiratory Infection Group, Liverpool School of Tropical Medicine, 4Institute of Infection and Global Health, University of Liverpool, 5Comprehensive Local Research Network, Royal Liverpool and Broadgreen University Hospital Trust, 6Department of Respiratory Research, University Hospital Aintree


JoVE 4345

 JoVE Medicine

The Use of Cystometry in Small Rodents: A Study of Bladder Chemosensation

1Laboratory of Experimental Urology, Department of Development and Regeneration, KU Leuven, Belgium, 2Laboratory for Ion Channel Research, Department of Cellular and Molecular Medicine, KU Leuven, Belgium, 3TRP Research Platform Leuven (TRPLe), KU Leuven, Belgium


JoVE 3869

 JoVE Behavior

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

1Department of Psychiatry and Behavioural Neurosciences, McMaster University, 2McMaster Integrative Neuroscience Discovery and Study, McMaster University, 3Department of Psychiatry, University of Calgary, 4Department of Psychology, Neuroscience & Behaviour, McMaster University


JoVE 52061

 JoVE Neuroscience

Non-restraining EEG Radiotelemetry: Epidural and Deep Intracerebral Stereotaxic EEG Electrode Placement

1Department of Neuropsychopharmacology, Federal Institute for Drugs and Medical Devices (Bundesinstitut für Arzneimittel und Medizinprodukte, BfArM), 2Molecular and Cellular Cognition Lab, German Center for Neurodegenerative Diseases (Deutsches Zentrum für Neurodegenerative Erkrankungen, DZNE)


JoVE 54216

 JoVE Behavior

Use of the Operant Orofacial Pain Assessment Device (OPAD) to Measure Changes in Nociceptive Behavior

1Department of Oral and Maxillofacial Surgery, University of Florida College of Dentistry, 2Department of Neuroscience, McKnight Brain Institute, University of Florida College of Medicine, 3Stoelting Co., 4Department of Orthodontics, University of Florida


JoVE 50336

 Science Education: Essentials of Lab Animal Research

Compound Administration II

JoVE Science Education

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN

Compound administration is often an integral component of an animal study. Many factors need to be evaluated to ensure that the compound is delivered correctly. The route of administration affects the mechanisms of absorption. The characteristics of the substance to be introduced (the pH, viscosity, and concentration) may dictate which route of administration is selected.1,2,3

 Science Education: Essentials of Sensation and Perception

Finding Your Blind Spot and Perceptual Filling-in

JoVE Science Education

Source: Laboratory of Jonathan Flombaum—Johns Hopkins University

In the back of everyone's eye is a small piece of neural tissue called the retina. The retina has photosensitive cells that respond to stimulation by light. The responses of these cells are sent into the brain through the optic nerve, a bundle of neural fibers. In each retina there is a place somewhere in the periphery where the outputs from retinal cells collect and the bundled optic nerve exits to the brain. At that location, there is no photosensitivity-whatever light reflects from the world and lands in that position does not produce a signal in the brain. As a result, humans have a blind spot, a place in the visual field for which they don't process incoming stimuli. However, people are not aware that they have blind spots; there is not an empty hole in the visual images in front of the eyes. So what do people see in their blind spots? The brain actually fills-in missing input based on the surroundings. This video demonstrates how to find a person's blind spot, and how to investigate the mechanisms of perceptual filling-in.

 JoVE Behavior

Combined Invasive Subcortical and Non-invasive Surface Neurophysiological Recordings for the Assessment of Cognitive and Emotional Functions in Humans

1Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine-University, 2Department of Neurology, Center for Movement Disorders and Neuromodulation, University Clinic Düsseldorf, 3Department of Neurosurgery, Functional Neurosurgery and Stereotaxy, Center for Movement Disorders and Neuromodulation, University Clinic Düsseldorf


JoVE 53466

 Science Education: Essentials of Experimental Psychology

The Factorial Experiment

JoVE Science Education

Source: Laboratories of Gary Lewandowski, Dave Strohmetz, and Natalie Ciarocco—Monmouth University

A factorial design is a common type of experiment where there are two or more independent variables. This video demonstrates a 2 x 2 factorial design used to explore how self-awareness and self-esteem may influence the ability to decipher nonverbal signals. This video leads students through the basics of a factorial design including, the nature of a factorial design and what distinguishes it from other designs, the benefits of factorial design, the importance and nature of interactions, main effect and interaction hypotheses, and how to conduct a factorial experiment.

 JoVE Neuroscience

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex

1Department of Neurosurgery, Columbia University Medical Center, New York Presbyterian Hospital, 2Department of Neurology, Columbia University Medical Center, New York Presbyterian Hospital, 3Columbia University Medical Center, New York Presbyterian Hospital, 4School of Medicine, King's College London


JoVE 52773

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