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Flight, Animal: The use of wings or wing-like appendages to remain aloft and move through the air.

Rodent Handling and Restraint Techniques

JoVE 10221

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN 

It has been demonstrated that even minimal handling of mice and rats is stressful to the animals. Handling for cage changing and other noninvasive procedures causes an increase in heart rate, blood pressure, and other physiological parameters, such as serum corticosterone levels. Fluctuations can continue for up to several hours. The methods of restraint required for injections and blood withdrawals also cause physiological changes that can potentially affect scientific data. Training in the proper handling of mice and rats is required to minimize the effects to the animals.1 Mice and rats can be restrained manually with restraint devices, or with chemical agents. Manual methods and the use of restraint devices are covered in this manuscript. All restraint methods include the process of lifting the animals from their home cage.


 Lab Animal Research

A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats

1Behavioral Neuroscience, Experimental and Biological Psychology, Philipps-Universität Marburg, 2Behavioral Neurosciences Institute (INeC), 3Thomas RECORDING GmbH, 4Department of Neurophysics, Philipps-Universität Marburg

Video Coming Soon

JoVE 56299


 JoVE In-Press

Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT)

1Division of Cardiovascular Medicine, University of Pennsylvania, Perelman School of Medicine, 2Department of Radiology, University of Pennsylvania, Perelman School of Medicine, 3Department of Dermatology, University of Pennsylvania, Perelman School of Medicine

JoVE 3777


 Medicine

In Vivo Tracking of Edema Development and Microvascular Pathology in a Model of Experimental Cerebral Malaria Using Magnetic Resonance Imaging

1Department of Neuroradiology, Heidelberg University Hospital, 2Division of Experimental Radiology, Department of Neuroradiology, Heidelberg University Hospital, 3NeuroImaging Centre Research, Department of Neuroscience, Ruhr-University Bochum, 4Centre for Infectious Diseases, Parasitology Unit, Heidelberg University Hospital, 5German Centre for Infection Research (DZIF), 6Department of Neuroradiology, University of Würzburg, 7Center for Childhood and Adolescent Medicine, General Pediatrics, Heidelberg University Hospital

JoVE 55334


 Medicine

Automated Measurement of Pulmonary Emphysema and Small Airway Remodeling in Cigarette Smoke-exposed Mice

1Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital - Harvard Medical School, 2Department of Respiratory Medicine, University of Cambridge - Addenbrooke's Hospital, 3Lung Transplant Program, Brigham and Women's Hospital - Harvard Medical School, 4COPD and IPF Programs, Lovelace Respiratory Research Institute

JoVE 52236


 Medicine

In Vitro Bioluminescence Assay to Characterize Circadian Rhythm in Mammary Epithelial Cells

1Department of Environmental and Occupational Health, School of Public Health, NIEHS Center for Environmental Exposures and Disease, Environmental and Occupational Health Sciences Institute, Rutgers University, 2Veterinary Drugs & Biologics Division, Animal and Plant Quarantine Agency

Video Coming Soon

JoVE 55832


 JoVE In-Press

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