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Journal / Biochemistry / Personlig peptid Arrays for påvisning af HLA…
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Biochemistry

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JoVE Journal Biochemistry
Personlig peptid Arrays for påvisning af HLA Alloantibodies i organtransplantation
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Personlig peptid Arrays for påvisning af HLA Alloantibodies i organtransplantation

Article DOI: 10.3791/56278-v • 08:07 min • September 6th, 2017
September 6th, 2017 •
1, 1, 1, 3, 2, 1
1Division of Nephrology and Hypertension, and the Center for Kidney Research and Therapeutics at the Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 2Surgery-Organ Transplantation, Northwestern University Feinberg School of Medicine, 3School of Biological Sciences and Medical Engineering, Southeast University

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Uoverensstemmelser i human leukocyt antigen (HLA) sekvenser mellem organdonor og modtagende par er den største årsag til antistof-medieret afvisning i organtransplantation. Her præsenterer vi brugen af brugerdefinerede antigen arrays, der er baseret på individuelle donorer HLA sekvenser at sonde anti-donor HLA alloantibodies i orgel modtagere.

Tags

Biokemi sag 127 organtransplantation antistof medierede transplantatets afvisning (AMR) Human leukocyt antigen (HLA) HLA uoverensstemmelse Alloantibody Antigen matrix SPOT syntese
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