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Cancer Research

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颅内插管植入小鼠连续局部区域嵌合抗原受体(CAR)T细胞输注
 
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颅内插管植入小鼠连续局部区域嵌合抗原受体(CAR)T细胞输注

Article DOI: 10.3791/64886-v 05:22 min February 24th, 2023
February 24th, 2023

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中枢神经系统(CNS)肿瘤是儿童癌症相关死亡的主要原因,基于局部免疫的疗法越来越多地在临床试验中为患者进行测试。该协议描述了在小鼠中植入局部区域套管的方法,用于靶向CNS肿瘤的免疫治疗输注的临床前评估。

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