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Was ist das Immunsystem?
The immune system comprises diverse biological structures and processes that protect the body from disease. These processes can be classified into…
Zellvermittelte Immunabwehr
The cell-mediated immune system is the host’s primary response against invasive bacteria and viruses that cause intracellular infections. It…
Humorale Immunreaktionen
The humoral immune response, also known as the antibody-mediated immune response, targets pathogens circulating in “humors,” or…
Antikörper-Struktur
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by…
Affinität und Avidität
Antibodies bind to toxins or substances on the surface of cells, bacteria, viruses, or fungi. The substance is called an antigen, and the precise…
Kreuzreaktivität
The ability of a single antibody to recognize multiple structurally similar epitopes is an important immune defense strategy that enables the host…
Allergische Reaktionen
We speak of an allergy when the immune system triggers a response against a benign foreign structure, like food, pollen or pet dander. These…
Entzündungen
In response to tissue injury and infection, mast cells initiate inflammation. Mast cells release chemicals that increase the permeability of…
Impfungen
Vaccination is the administration of antigenic material from pathogens to confer immunity against a specific microorganism. Vaccination primes the…
Orthotopen Implantation und der peripheren Immunzellenüberwachung in der II-45 Syngene Rat Mesotheliom Modell
The enormous upsurge of interest in immune-based treatments for cancer such as vaccines and immune checkpoint inhibitors, and increased understanding…
Die Bestimmung Unterdrückung des Immunsystems gegen ZNS-Schutz für pharmakologische Interventionen im Bereich der Autoimmun- Demyelinisierung
A major hallmark of the autoimmune demyelinating disease multiple sclerosis (MS) is immune cell infiltration into the brain and spinal cord resulting…
Live-Imaging von angeborenen Immun und Präkanzeröse Zell-Interaktionen unter Verwendung eines induzierbaren Gal4 / UAS Expression System in Zebrafisch-Larven Haut
Here we describe a method to conditionally induce epithelial cell transformation by the use of the 4-Hydroxytamoxifen (4-OHT) inducible…
Injektionen von Lipopolysaccharid in Mäuse, Eingang des mikrobiellen gewonnenen Erzeugnisse nach Darmbarriere Verletzung zu imitieren
The intestinal epithelial barrier separates the host from the microbiota that is normally tolerated or ignored. The breach of this barrier results in…

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