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Antifouling Self-assembled Monolayers on Microelectrodes for Patterning Biomolecules

Article DOI: 10.3791/1390-v • 10:27 min • August 25th, 2009
August 25th, 2009 •
1, 1, 2
1Department of Physics, Texas A&M University (TAMU), 2Department of Biomedical Engineering, Texas A&M University (TAMU)

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We present a procedure for forming a poly(ethylene glycol) self-assembled monolayer (PEG-SAM) on a silicon substrate with gold microelectrodes. The PEG-SAM is formed in a single step and prevents biofouling on silicon and gold surfaces. Electrophoresis is then used for patterning biomolecules down to the nanoscale.

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Antifouling Self-assembled Monolayers Microelectrodes Patterning Biomolecules Poly(ethylene Glycol) (PEG) Trimethoxysilane Silicon Substrate Gold Surfaces Biofouling Prevention Positive-tone Lithography Electrophoretic Migration Flow Chamber Epifluorescence Microscopy Biomolecule Patterning Electron Beam Lithography Nanoscale Patterning
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