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Using Skin Biopsies to Generate Patient-Derived Podocytes

Article DOI: 10.3791/200092-v • 02:41 min • May 26th, 2023
May 26th, 2023 •
1, 1,2
1Department of Nephrology and Hypertension, University Hospital Erlangen, Friedrich-Alexander University (FAU) Erlangen-Nürnberg, 2Research Center on Rare Kidney Diseases (RECORD), University Hospital Erlangen

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Patient-derived Podocytes Skin Biopsies Episomal Reprogramming Human-induced Pluripotent Stem Cells In Vivo Podocytes Podocyte Specific Marker Terminally Differentiated Cells Conditionally Immortalized Podocytes Dedifferentiated Phenotype Induced Pluripotent Stem Cells Typical Podocyte Morphology Patient-specific Stem Cells Genetic Podocyte Disease Personalized Diseased Cells Ex Vivo Model Podocyte Diseases Therapeutic Substances
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