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超声造影有针对性的治疗胶质瘤的小鼠通过药物轴承纳米粒子交付和微血管消融
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Contrast Ultrasound Targeted Treatment of Gliomas in Mice via Drug-Bearing Nanoparticle Delivery and Microvascular Ablation
DOI:

14:10 min

December 15, 2010

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Chapters

  • 00:05Title
  • 02:02Introduction
  • 02:37Preparation of the Animal Model
  • 02:59Nanoparticle Fabrication
  • 06:07In Vivo Ultrasound to Perform Targeted Drug Delivery
  • 07:12Nanoparticle Biodistribution
  • 10:44Tumor Growth Rate
  • 11:22Tumor Processing and Analysis
  • 12:21Representative Results
  • 13:24Conclusion

Summary

Automatic Translation

微泡Insonation是很有前途的战略肿瘤消融时间平均减少声学权力,以及为靶向给药疗法。本研究的目的是开发低占空比超声脉冲战略和nanocarriers最大限度地发挥非热微血管消融和有效载荷运送到皮下C6脑胶质瘤。

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