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Journal / Neuroscience / Optik Sinir transeksiyonu: Santral Sinir Sistemi…
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JoVE Journal Neuroscience
Optik Sinir transeksiyonu
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Optik Sinir transeksiyonu: Santral Sinir Sistemi Yetişkin Nöron Apoptoz Bir Model

Article DOI: 10.3791/2241-v • 12:06 min • May 12th, 2011
May 12th, 2011 •
*1, *1, 1
1Department of Surgery, University of Toronto
* These authors contributed equally

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Optik Sinir transeksiyonu yetişkin MSS yaralanma yaygın olarak kullanılan bir model. Retina ganglion hücrelerinin yüzde doksanı (RGCs) olan aksonlar tamamen axotomy sonra 14 gün içinde ölürler (axotomy) transeksiyon. Bu model, deneysel manipülasyonlar kolayca mükellef ve yüksek tekrarlanabilir.

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Nörobilim sayı 51 Merkezi Sinir Sistemi Retina Apoptoz Retina Ganglion Hücre Axotomy Optik Sinir transeksiyonu Rat Retrograd Etiketleme Sıçan Modeli
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