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Eksperimentel Generering af Carcinoma-associerede fibroblaster (cafeer) fra Human brystkirtler fibroblaster
 
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Eksperimentel Generering af Carcinoma-associerede fibroblaster (cafeer) fra Human brystkirtler fibroblaster

Article doi: 10.3791/3201
October 25th, 2011

Summary October 25th, 2011

Please note that all translations are automatically generated.

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Carcinoma-associeret fibroblaster (cafeer) rig på myofibroblasts stede i tumor stroma, spiller en vigtig rolle som drivkraft for tumorprogression. Vi udviklede en coimplantation tumor xengraft model for eksperimentelt at generere cafeer fra menneskelige brystkirtler fibroblaster. Protokollen beskriver, hvordan man etablerer CAF myofibroblasts, der erhverver en evne til at fremme tumorgenese.

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