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Biomarkører i en dyremodell for Avslører Neural, Hematologic, og Behavioral korrelerer av PTSD
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Biomarkører i en dyremodell for Avslører Neural, Hematologic, og Behavioral korrelerer av PTSD

Article DOI: 10.3791/3361
October 10th, 2012 •
1, 2, 1, 1, 1, 2, 1, 1, 2, 1
1Department of Psychiatry, Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, Maryland, 2Department of Gene and Protein Biomarkers, GenProMarkers, Inc.

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October 10th, 2012

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Vi beskriver en rotte modell av post traumatisk stress lidelse (PTSD) som avslører vedvarende endringer i nevroendokrine funksjon og forsinket langsiktig, overdrevet frykt respons, karakteristisk for PTSD-pasienter. Dyret modellen og metoder beskrevet her er nyttige for å korrelere biomarkører i hjernen kjerner, som er mekanistisk, men kan ikke måles hos pasienter med biomarkører i perifere hvite blodceller, noe som kan.

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