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Funktionelle Bildgebung Brown Fat in Mäusen mit FDG micro-PET/CT

Article DOI: 10.3791/4060
November 23rd, 2012 •
1, 2, 1
1Department of Translational Imaging, The Methodist Hospital Research Institute, Houston, 2Diabetes Research Center, The Methodist Hospital Research Institute, Houston

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November 23rd, 2012

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Verfahren zur funktionellen Bildgebung von Maus braunen Fettgewebe (BAT) beschrieben, bei dem kalte-stimulierte Aufnahme von 18F-Fluorodeoxyglucose (FDG) in BAT nichtinvasiv beurteilt mit einer standardisierten micro-PET/CT Protokoll ist. Diese Methode ist robust und sensibel auf Unterschiede in der BAT-Aktivitäten in Maus-Modellen erkennen.

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