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En minut, Sub-ett-Watt fototermisk tumör Ablation Använda Porphysomes, Intrinsic Multifunktionell Nanovesicles
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1Department of Pharmaceutical Sciences,University of Toronto, 2The Institute of Biomaterials and Biomedical Engineering,University of Toronto, 3Ontario Cancer Institute,Campbell Family Institute For Cancer Research and Techna Institute, 4Department of Biomedical Engineering,University at Buffalo, The State University of New York
Chapters
- 00:05Title
- 01:41Preparation of Porphysomes
- 05:27In vivo Photothermal Therapy
- 07:43Porphysome Characterization and Tumor Treatment Results
- 09:23Conclusion
Vi utvecklade nya inneboende multifunktionella nanovesicles kallas porphysomes, som har strukturen beroende fluorescens självsläckning och unika fototermiska egenskaper, vilket fungerar som potenta fototermisk terapimedel. Vi formulerade porphysomes använder högtrycks extrudering och undersökt deras fototermisk terapi effektivitet i en xenograft tumörmodell.
Tags
PorphysomesPhotothermal Tumor AblationIntrinsic Multifunctional NanovesiclesPhotosensitizerPyropheophorbide αPhospholipidLiposome-like Spherical VesiclesExtinction CoefficientsFluorescence Self-quenchingPhotothermal EfficacyHigh Pressure ExtrusionTumor Temperature IncreaseLaser IrradiationThermal AblationEscharsPhotothermal Therapy (PTT)
