The Tomato/GFP-FLP/FRT method involves visualizing mosaic photoreceptor cells in living Drosophila. It can be used to follow individual photoreceptor cell fates in the retina for days or weeks. This method is ideal for studies of retinal degeneration and neurodegenerative diseases or photoreceptor cell development.
Dourlen, P., Levet, C., Mejat, A., Gambis, A., Mollereau, B. The Tomato/GFP-FLP/FRT Method for Live Imaging of Mosaic Adult Drosophila Photoreceptor Cells. J. Vis. Exp. (79), e50610, doi:10.3791/50610 (2013).