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Split-e-pool Sintesi e caratterizzazione di peptidi Terziario Ammide Biblioteca
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Split-e-pool Sintesi e caratterizzazione di peptidi Terziario Ammide Biblioteca

Article DOI: 10.3791/51299-v • 13:37 min • June 20th, 2014
June 20th, 2014 •
1, 1
1Scripps Florida, The Scripps Research Institute

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Peptide ammidi terziarie (PTA) sono una superfamiglia di peptidomimetici che includono ma non sono limitate a peptidi, peptoids e peptidi N-metilato. Qui si descrive un metodo sintetico che combina split-e-pool e le strategie sub-monomeri per sintetizzare un one-tallone biblioteca un composto di PTA.

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Chimica sintesi Split-e-pool peptide ammide terziaria PTA peptoid high-throughput screening biblioteca combinatoria fase solida trifosgene (BTC) una perlina di un composto OBOC
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