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JoVE Journal
Biology

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高通量MHC II类分子结合分析抗原表位肽的定量分析
 
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高通量MHC II类分子结合分析抗原表位肽的定量分析

Article DOI: 10.3791/51308-v 07:59 min March 25th, 2014
March 25th, 2014

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Summary

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Click here for the English version.

生物化学测定重组人MHC II类分子可提供快速,定量分析上市免疫原性表位的识别,缺失或设计。这里,缩放到384孔板的肽-MHC II类分子结合测定法进行说明。这种成本效益的格式应该证明在蛋白质去免疫和疫苗的设计和开发领域非常有用。

Tags

生物化学,85期,免疫,免疫原性蛋白,MHC II类分子,T细胞表位,高通量筛选,去免疫,疫苗设计
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