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Assessment of Vascular regeneração no SNC Usando o rato Retina
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Assessment of Vascular regeneração no SNC Usando o rato Retina

Article DOI: 10.3791/51351 • 07:32 min
June 23rd, 2014 •
1, 2, 3, 2, 2, 1,2,3
1Department of Neurology-Neurosurgery, McGill University, 2Department of Biochemistry, Maisonneuve-Rosemont Hospital Research Centre, University of Montréal, 3Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montréal

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June 23rd, 2014

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A retina de roedores tem sido reconhecida como uma janela de acesso para o cérebro. Neste documento técnico que proporcionam um protocolo que utiliza o modelo de ratinho de retinopatia induzida por oxigénio para estudar os mecanismos que levam à insuficiência de regeneração vascular dentro do sistema nervoso central após a lesão isquémica. O sistema descrito também pode ser aproveitada para explorar estratégias para promover o crescimento de vasos sanguíneos funcionais dentro da retina e do SNC.

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