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Journal / Immunology and Infection / In tempo reale Imaging del endoteliali giunzioni…
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Immunology and Infection

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JoVE Journal Immunology and Infection
In tempo reale Imaging del endoteliali giunzioni cellula-cellula Durante neutrofili Trasmigrazione Sotto fisiologico flusso
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In tempo reale Imaging del endoteliali giunzioni cellula-cellula Durante neutrofili Trasmigrazione Sotto fisiologico flusso

Article DOI: 10.3791/51766-v • 11:26 min • August 14th, 2014
August 14th, 2014 •
*1, *1, 1, 1
1Department of Molecular Cell Biology, Sanquin Research and Landsteiner Laboratory, AMC at University of Amsterdam
* These authors contributed equally

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I leucociti attraversano il monostrato endoteliale utilizzando il paracellulare o il percorso transcellulare. Abbiamo sviluppato un test semplice per seguire la distribuzione di giunzionale endogena VE-caderina e PECAM-1 durante la migrazione dei leucociti transendoteliale sotto flusso fisiologico di discriminare tra le due vie di trasmigrazione.

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Immunologia leucociti ombelicale umano Vena cellule endoteliali (HUVEC) trasmigrazione VE-caderina PECAM-1 endotelio transcellulare paracellulare
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