Muscle sensory neurons are involved in proprioceptor signaling and also report on metabolic state and injury related events. We describe an adult mouse in vitro muscle-nerve preparation for studies on stretch-activated muscle afferents.
Franco, J. A., Kloefkorn, H. E., Hochman, S., Wilkinson, K. A. An In Vitro Adult Mouse Muscle-nerve Preparation for Studying the Firing Properties of Muscle Afferents. J. Vis. Exp. (91), e51948, doi:10.3791/51948 (2014).