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JoVE Journal
Immunology and Infection
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造型埃博拉病毒的生命周期在生物安全二级条件下的病毒样颗粒包含Tetracistronic小基因组
 
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造型埃博拉病毒的生命周期在生物安全二级条件下的病毒样颗粒包含Tetracistronic小基因组

Article DOI: 10.3791/52381-v 10:11 min September 27th, 2014
September 27th, 2014

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Summary

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Click here for the English version.

与感染埃博拉病毒的工作仅限于生物安全4级实验室。 Tetracistronic复制和转录能力的病毒样颗粒含有微型基因组 - (trVLPs)代表一个生命周期建模系统,使我们能够安全地模拟多种传染病周期下的生物安全级别2的条件下,对​​埃博拉病毒组件完全依赖。

Tags

传染病,第91,出血热,病毒,Mononegavirales感染,埃博拉病毒,纤维病毒,生命周期建模系统,微型基因组,反向遗传,病毒样颗粒,复制,转录,含苞待放,形态,进入
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